Protein Alignment Ranbp21 and LOC100486598

DIOPT Version :10

• Sequence 1: NP_608339.2
• Gene: Ranbp21 / 32970
• FlyBaseID: FBgn0031051
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: XP_031757696.1
• Gene: LOC100486598 / 100486598
• XenbaseID: XB-GENE-29078411
• Length: 1245
• Species: Xenopus tropicalis
• Alignment Length: 1259
• Identity: 360/1259 - (28%)
• Similarity: 619/1259 - (49%)
• Gaps: 125/1259 - (9%)

  Fly    10 LAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLIE 74
            |...|..|:.::|:|.:.|:.|.||:..||.|||.||:|...||.|::...| ..||||||.::|
 Frog    54 LCGRLVRALTVIMDPKSSQEGRQEAHKFCEEFKERSPLCVPCGLQLSNRSHS-PCVRHFGLHVLE 117

  Fly    75 YTIKYRWNCITHEEKVYIKDNAIKMLNVGVGP-AEDRSLLPTKDALSRIIVEMIKREWPQQWSDL 138
            :.||:|||.::.:::|::|::.:.:::.|:.| .|::..:  ||.::|::||:||||||..|.|:
 Frog   118 HVIKFRWNVMSVDDRVFVKNSVMLLISHGIHPILEEKGHI--KDVIARVVVEIIKREWPWNWPDM 180

  Fly   139 LPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLRLVEQ 203
            :.||:.....|:||.|||:.:.|||.|::..|:|....| .||:::.|..||:.||.|.:.::::
 Frog   181 VNELACLGNFGDAQMELVMFILLRLAEEIGPLETRPICQ-PKDLHELLKENMDKIFAFVVTILQR 244

  Fly   204 HVTAFRETTRLCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAFQC 268
            .|...:..|:        ...||....|.||:|:::.:..:.||:.|..|:..||:|||....|.
 Frog   245 CVPNCQNLTQ--------GQFRVAAAALRTLAGYIKCLPTRLIMADNCTLLWLLCVLLNVPELQM 301

  Fly   269 NAAECLAQITNRKG-QTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQVL 332
            .|||||....|:|| ..:||.|||.||.|:.||||..|:|: ||  |....|::...||.:.|:|
 Frog   302 EAAECLLFAVNKKGLLLEERVPLLILFREDALRYILTAAQL-AD--SDPLQERNYVILKMIGQIL 363

  Fly   333 NGMAQQLVALWGKDDAT----QRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKD 393
            ..:..||.|     ..|    :.|.:.:..||.||.|.:||||.|:..:|.:|..|..|...|.|
 Frog   364 CDLGNQLCA-----QVTAFEVKTPENFDRYLEALLSLTRHPSLFLTSLAAEVWGTLFNHRVLSHD 423

  Fly   394 FAMVNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYF--FR-------- 448
            ..:...||.::......|||:.||:..:||:.    .|.|::.|.:.|:..:|  ||
 Frog   424 PQLTAAIPDVLRAAMVSIVKVGYPSMDNSPSC----EYSRMDFDDDIEFNTFFLSFRKQMGIVVR 484

  Fly   449 --CRTDFLEIFRLATLVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVSCSVLDPVYLEWDAL 511
              ||.|...:..:||            :|::.:|............||...||...|.:|.|:|:
 Frog   485 SLCRLDTRTVLHVAT------------EWMRHQLSAPLDPGPHNATSGEALCSPHSPSFLHWEAM 537

  Fly   512 VSVLDGVLSRIL--LVAERPSVPAGLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQIT 574
            ......|.:.:.  |.||...:..|:.||::.:..||.:||..|.:|:.:|.|..|:
 Frog   538 SFFCSEVFAPLCRPLSAEEVLLTQGVSLLQQVISYETKDPLIVSCVLTNLSTLLPFI-------- 594

  Fly   575 ATNCVAMSGVSLLPRVLDKIFRALVMKPPNELEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPV 639
                  ..|..|||.::.|:..|......:.: ||......|:|..|::||..:..::|.|:.|.
 Frog   595 ------RHGSDLLPLMVSKLLSAAGFADTDAV-KVPRTLLMNIRSCASALLQTICIRFPDLVGPH 652

  Fly   640 FEQINGHVELLLKEPGKHQ-LCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWLA-- 701
            ||.::..::.||   |:.| |....|..|..||:|.||||.::.||...:|.::|...:..|:
 Frog   653 FEVLHTRIKALL---GQEQLLADAERCALMGALVLASNHFKNYNRQRSILEELLQPAVSMLLSEE 714

  Fly   702 FGDALKSPLDFMSFVGLDKPPIFAVEGAVT--LQNRSRLLDALHVVLGVVKRCTWPDDPERAQRG 764
            ....|..|.:|:||:..:.|.....|..|.  ..:.|:|....:..|..:::...|...:.|:.|
 Frog   715 MQRVLSGPSEFISFLRANNPGSENQEEGVDGGRLSYSKLCYCAYTFLAAIRKSRRPIIFKEAKAG 779

  Fly   765 GFVIGCTELGNPICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSE-----GYRGIHGMME 824
            |||.|||..|..:.:||....::.:|..:|.|:|.:|.|:.||.:..::|     ........:|
 Frog   780 GFVKGCTPDGVAMLQNPCAGELLKVLDRLLVLIRTMNSLYLPEVMTKMAETSLKMAETSQSCELE 844

  Fly   825 HEKKLLMGICALPTDPLDTTIRSEP----TAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLM 885
            ...|.:|. |:.|       |..|.    |..|::|.....:.:.|..::|..|||:..:.|.:.
 Frog   845 MGNKSIMD-CSQP-------IMGESGPPVTMPEQLQGPYNSLYKACCQILGKCGPSMPHEFYSVP 901

  Fly   886 GLSDAIVTNVFSRMDLVPDYRLRPIIRVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRW 950
            .|:..::::.|:.:|.|.|..||.|:.....|.::.||...|.||.:|:...|...:.:||:::|
 Frog   902 DLASRLLSSAFTNLDYVSDLHLRHIVIDLVTPLIFYCPSKKYQSVALPILGPLLMSLYQRLSQKW 966

  Fly   951 IYIASLYESGQLDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANAN----- 1010
            :.|.....:.:.| .:.:..|..:|.:.|.|:|..:..:.|..:     |.|....::|:
 Frog   967 LCINQRTTASEED-LLEEESESQDDLMVRLLSRTVVQFIYICCM-----ASHTTYQSDADYRIAP 1025

  Fly  1011 --SNSVAMENEEHSMDSAPQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGM- 1072
              ..:.|.|.||:.:..|..::.::|..|    |.||..||.|..:...:|:....::.|.|..
 Frog  1026 RVEQAEADEEEENLILMAAAAKVLKSLAL----SKLGQFLLSNEEVYTALLLMAYSSLMWKDPQT 1086

  Fly  1073 CSMKAVNIAAPVMRFLAAEKLMDENKAVTAFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQ 1137
            |:|.|..:...::..:.|..| ..:.||..|.:||.|:|.:|..::....||.|..:||..|||:
 Frog  1087 CNMAATRLCWSLLSQMMAVSL-PADAAVCYFASVLGGLQANGHCKSCTDPLVRLAFRFYVALRPK 1150

  Fly  1138 FPILSEVLQHIPSVNAADIQKFDEKIAVAPVKGNKVDRAKKDIFKKLTAQLVGRSVNQLFRHEVQ 1202
            :|.|..:::.:|::....:::||:.:....::.|  :|..::.|.||.:....:.:...| ::|.
 Frog  1151 YPELHGLMEQVPNIQRDTLERFDKNLLSPDLEIN--ERMCREQFAKLLSGCTEKPLADQF-YKVH 1212

  Fly  1203 IANLPPMQSHKAKGSMGTTADIMD 1226
            |.:||       .|..||:..:::
 Frog  1213 IQHLP-------AGFKGTSGPVLE 1229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ranbp21	NP_608339.2	IBN_N	34..101	CDD:397745	27/66 (41%)
		Xpo1	116..274	CDD:462459	57/157 (36%)
		Exportin-5	319..1196	CDD:437105	235/916 (26%)
LOC100486598	XP_031757696.1	IBN_N	78..145	CDD:197981	27/67 (40%)
		Xpo1	156..307	CDD:462459	57/161 (35%)
		Exportin-5	350..1208	CDD:437105	235/917 (26%)