Protein Alignment Arp10 and ACTL6A

DIOPT Version :9

• Sequence 1: NP_001285452.1
• Gene: Arp10 / 32969
• FlyBaseID: FBgn0031050
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 80/429 - (18%)
• Similarity: 150/429 - (34%)
• Gaps: 110/429 - (25%)

  Fly    14 IVLDIGTAYTKLGFAAEAYPRKIMPTEVVMT---------------------------TTGIRKR 51
            :|.|||:...:.|:|.|..|:...||.:.|.                           |..:|..
Human    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVP 78

  Fly    52 LFDYDTPEELYDQLV---DFLQTI----FFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVH 109
            ..:.:....|.:.:|   |..|.|    :..|:.........::.|..:.:...||.|..::|.|
Human    79 RENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEH 143

  Fly   110 FDVSSVLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGGSAIHAEIKR 174
            :::.:.......::........|.|::|.|.:.|:.:||..|..:..........|..|..:.:.
Human   144 YNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRE 208

  Fly   175 QLVESGV------------------------KESL--LTES--------VLEDIKVRTCFVTTME 205
            ...|..:                        ||.|  :|.|        |::|.:.....|:.
Human   209 LFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVLQVSD-- 271

  Fly   206 RAKARANGDENQPTPAPDVDYIVSDNDAVIQVP-------GLLRESAYEIMFEASNERD------ 257
                 :..||......|.|.|         :.|       |..|....|.:|:.||.:.
Human   272 -----STYDEQVAAQMPTVHY---------EFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTM 322

  Fly   258 -SLPHLILRSILDCTLDVRRALVESVFLVGGGSMVQGLLARLRQELQHLLTEDPFYAERFHGELQ 321
             .:.|::..|:..|.:|:|..|..||.:.||.:::|....||.:||          :::....::
Human   323 LGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNREL----------SQKTPPSMR 377

  Fly   322 FKFF--NAVGKQNFTAWLGGALCGATDLIQTRSLVKETY 358
            .|..  |...::.|::|:||::..:....|...:.|:.|
Human   378 LKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEY 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp10	NP_001285452.1	ACTIN	11..340	CDD:214592	76/409 (19%)
		NBD_sugar-kinase_HSP70_actin	12..367	CDD:302596	80/429 (19%)
ACTL6A	NP_004292.1	Actin	11..429	CDD:394979	80/429 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900