DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp10 and Actl7b

DIOPT Version :9

Sequence 1:	NP_001285452.1	Gene:	Arp10 / 32969	FlyBaseID:	FBgn0031050	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_079547.2	Gene:	Actl7b / 11471	MGIID:	1343053	Length:	418	Species:	Mus musculus

Alignment Length:	379	Identity:	83/379 - (21%)
Similarity:	149/379 - (39%)	Gaps:	60/379 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IVLDIGTAYTKLGFAAEAYPRKIMPTEVVMTTTGIRKRLFDYDTPEEL----------------- 61
            :|:|:|:.|.|.|:|.|  ||   ||..:.:|.|.|......|..:..
Mouse    54 LVIDLGSQYCKCGYAGE--PR---PTYFISSTVGKRSAEMAADAGDNFKETYVGHELLNMEASLK 113

  Fly    62 ------------YDQLVDFLQTIFFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVHFDVSS 114
                        :|.:.:..:.||...:.:.|:|...::.:.....|..||..|.:||..|.:.:
Mouse   114 LVNPLKHGVVVDWDCIQNIWEYIFHTAMKIMPEEHAVLVSDPPLSPTSNREKYAELLFETFGIPA 178

  Fly   115 VLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGGSAIHAEIKRQLVES 179
            :......|:::.:....:.|||:.|:..:.|:|:..|..:........|.|..:...:.:.|.|:
Mouse   179 MHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPSRVDYAGCDLTNYLMQLLNEA 243

  Fly   180 GVKESLLTESVLEDIKVRTCFVTTMERAKARANGDENQPTPAPDVDYIVSDNDAVIQVPGLLRES 244
            |.|.|.....::|.||.:.|:...:...:.....||..      |||.:.|. .:|.: |..|..
Mouse   244 GHKFSDDHLHIIEHIKKKCCYAALLPEEEMSLGLDELH------VDYELPDG-KIITI-GQERFR 300

  Fly   245 AYEIMFEAS---NERDSLPHLILRSILDCT-LDVRRALVESVFLVGGGSMVQGLLARLRQELQHL 305
            ..|::|:.|   ..:..||.|....:..|. ...:..:..:|.|.||.:|:.|...|.::||..|
Mouse   301 CSEMLFKPSLVGCTQPGLPELTATCLARCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLL 365

  Fly   306 LTED-PFYAERFHGELQFKFFNAVGKQNFTAWLGGALCGATDLIQTRSLVKETY 358
            ...| |..|             |..::..:.|.||::..:....|...:.||.:
Mouse   366 CPGDSPTVA-------------AAPERKTSVWTGGSILASLQAFQQLWVSKEEF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp10	NP_001285452.1	ACTIN	11..340	CDD:214592	79/359 (22%)
Arp10	NP_001285452.1	NBD_sugar-kinase_HSP70_actin	12..367	CDD:302596	83/379 (22%)
Actl7b	NP_079547.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		ACTIN	52..418	CDD:214592	83/379 (22%)
		NBD_sugar-kinase_HSP70_actin	53..418	CDD:302596	83/379 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D964605at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910