Protein Alignment Arp10 and Acta1

DIOPT Version :10

• Sequence 1: NP_608338.1
• Gene: Arp10 / 32969
• FlyBaseID: FBgn0031050
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_033736.1
• Gene: Acta1 / 11459
• MGIID: 87902
• Length: 377
• Species: Mus musculus
• Alignment Length: 388
• Identity: 84/388 - (21%)
• Similarity: 155/388 - (39%)
• Gaps: 68/388 - (17%)

  Fly    10 EKPPIVLDIGTAYTKLGFAAEAYPRKIMPTEV-------VMTTTGIR----------KR------ 51
            |...:|.|.|:...|.|||.:..||.:.|:.|       ||...|.:          ||
Mouse     6 ETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLK 70

  Fly    52 -------LFDYDTPEELYDQLVDFLQTIFFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVH 109
                   :.::|..|:::..       .|:..|.|:|:|...:|.|........||.:.:::|..
Mouse    71 YPIEHGIITNWDDMEKIWHH-------TFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFET 128

  Fly   110 FDVSSVLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGGSAIHAEIKR 174
            |:|.::......:::|......|.:|:|.|...|..:|::.|..:..|.......|..:...:.:
Mouse   129 FNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMK 193

  Fly   175 QLVESGVKESLLT---ESVLEDIKVRTCFVT---TMERAKARANGDENQPTPAPDVDYIVSDNDA 233
            .|.|.|.  |.:|   ..::.|||.:.|:|.   ..|.|.|.::....:....||...|...|:
Mouse   194 ILTERGY--SFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNE- 255

  Fly   234 VIQVPGLLRESAYEIMFEAS---NERDSLPHLILRSILDCTLDVRRALVESVFLVGGGSMVQGLL 295
                    |....|.:|:.|   .|...:......||:.|.:|:|:.|..:..:.||.:|..|:.
Mouse   256 --------RFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIA 312

  Fly   296 ARLRQELQHLLTEDPFYAERFHGELQFKFFNAVGKQNFTAWLGGALCGATDLIQTRSLVKETY 358
            .|:::|:..|..          ..::.|.. |..::.::.|:||::..:....|...:.|:.|
Mouse   313 DRMQKEITALAP----------STMKIKII-APPERKYSVWIGGSILASLSTFQQMWITKQEY 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp10	NP_608338.1	ASKHA_NBD_Arp10	14..370	CDD:466813	83/384 (22%)
Acta1	NP_033736.1	ASKHA_NBD_actin	8..372	CDD:466823	83/386 (22%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	112..125		2/12 (17%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	360..372		2/5 (40%)