Protein Alignment Arp10 and ACTR3

DIOPT Version :10

• Sequence 1: NP_608338.1
• Gene: Arp10 / 32969
• FlyBaseID: FBgn0031050
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_005712.1
• Gene: ACTR3 / 10096
• HGNCID: 170
• Length: 418
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 100/434 - (23%)
• Similarity: 168/434 - (38%)
• Gaps: 97/434 - (22%)

  Fly    12 PPIVLDIGTAYTKLGFAAEAYPRKIMPTEVVMTTTG---------IRKRLFDYD---------TP 58
            |..|:|.||.|||||:|....|:.|:|:.:.:..:.         :.|.:.|.|         .|
Human     6 PACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKP 70

  Fly    59 E------------ELYDQLVDFLQTIFFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVHFD 111
            .            |.:|.:..|::.:.||:|...|::..|:|.|....:...||..|.::|..|:
Human    71 TYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFN 135

  Fly   112 VSSVLFVPVHLIALS-----------TLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGG 165
            |..:......::||:           ||   |..|:|.|...|.|:||..|..|          |
Human   136 VPGLYIAVQAVLALAASWTSRQVGERTL---TGTVIDSGDGVTHVIPVAEGYVI----------G 187

  Fly   166 SAI-HAEIKRQLVESGVKESLLTESVLEDIKVRTCFVTTMERAKARANGDENQPTPAPDV--DYI 227
            |.| |..|      :|...:...:.:|.|.:|......::|.|||   ..|......||:  ::.
Human   188 SCIKHIPI------AGRDITYFIQQLLRDREVGIPPEQSLETAKA---VKERYSYVCPDLVKEFN 243

  Fly   228 VSDNDA---VIQVPGLLRESAYEIMFEASNERDSLPHLILRS------------------ILDCT 271
            ..|.|.   :.|..|:...|..|...:...||...|.:....                  |.:|.
Human   244 KYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCP 308

  Fly   272 LDVRRALVESVFLVGGGSMVQGLLARLRQELQHLLTEDPFYAERFH-GELQFKFFNAV----GKQ 331
            :||||.|.:::.|.||.:|.:....||:::|:..:......:|... |.|:.|..:..    ..|
Human   309 IDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQ 373

  Fly   332 NFTAWLGGALCGATDLIQTRSLVKETYLKSEHVPDWSNLCDNRP 375
            .:..|.||::     |..|....:..:.|.::.....::|.:.|
Human   374 RYAVWFGGSM-----LASTPEFYQVCHTKKDYEEIGPSICRHNP 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp10	NP_608338.1	ASKHA_NBD_Arp10	14..370	CDD:466813	97/425 (23%)
ACTR3	NP_005712.1	ASKHA_NBD_Arp3-like	7..410	CDD:466822	98/429 (23%)