DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arp10 and POTEB2

DIOPT Version :9

Sequence 1:NP_001285452.1 Gene:Arp10 / 32969 FlyBaseID:FBgn0031050 Length:378 Species:Drosophila melanogaster
Sequence 2:NP_001264232.1 Gene:POTEB2 / 100287399 HGNCID:48327 Length:544 Species:Homo sapiens


Alignment Length:208 Identity:46/208 - (22%)
Similarity:72/208 - (34%) Gaps:58/208 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 VENVFGSTVLR-------ETLARVLFVH-FDVSS-------VLFVPVH----------------L 122
            :::.:|:|.|.       :.:|:.|.:: .|:.|       .|.:.||                |
Human   197 IQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANL 261

  Fly   123 IALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQS------YGGSAIHAEIKRQLVESGV 181
            .||.... .|||::.|.....|::.:.....:..:.:|.|      |..|:.|..|...|.:...
Human   262 NALDRYG-RTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKE 325

  Fly   182 KESLLTES----VLEDIKVRTCFVTTMERAKARANGDEN-QPTPAPDVDYIVSDNDAVIQVPGLL 241
            |:.|...|    ..:|:|:      |.|....|....|| ||........|..|.|         
Human   326 KQMLKISSENSNPEQDLKL------TSEEESQRLKVSENSQPEKMSQEPEINKDCD--------- 375

  Fly   242 RESAYEIMFEASN 254
            ||...||....||
Human   376 REVEEEIKKHGSN 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp10NP_001285452.1 ACTIN 11..340 CDD:214592 46/208 (22%)
NBD_sugar-kinase_HSP70_actin 12..367 CDD:302596 46/208 (22%)
POTEB2NP_001264232.1 ANK 130..255 CDD:238125 10/57 (18%)
ANK 1 135..167
ANK repeat 137..166 CDD:293786
ANK 2 168..200 0/2 (0%)
ANK repeat 168..199 CDD:293786 0/1 (0%)
ANK 196..320 CDD:238125 24/123 (20%)
ANK 3 201..233 7/31 (23%)
ANK repeat 201..232 CDD:293786 7/30 (23%)
ANK 4 234..266 6/31 (19%)
ANK repeat 234..265 CDD:293786 5/30 (17%)
ANK 5 267..299 5/32 (16%)
ANK repeat 267..298 CDD:293786 5/31 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..457 19/72 (26%)
SMC_N <412..>542 CDD:330553
CCDC144C 489..>542 CDD:317340
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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