DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12237 and Phospho2

DIOPT Version :9

Sequence 1:	NP_608336.1	Gene:	CG12237 / 32967	FlyBaseID:	FBgn0031048	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_082797.1	Gene:	Phospho2 / 73373	MGIID:	1920623	Length:	241	Species:	Mus musculus

Alignment Length:	234	Identity:	83/234 - (35%)
Similarity:	133/234 - (56%)	Gaps:	4/234 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LAAFDFDHTIVSQNTDTVVRDLLPTEVTSAKVNELVENDCWTEYMAEVFRLLHEQQVSEARIRDT 93
            |..||||:||:..|:||.:....|.:....::.:..:...|||:|..||:.|.::.|....::..
Mouse     4 LLVFDFDNTIIDDNSDTWIVQCAPDKKLPIELQDSYQKGLWTEFMGRVFKYLRDEGVKADELKRA 68

  Fly    94 IRGIPEVPGFVRLIKHL-AKRLHYDLIIISDSNSVFIDEWLRAHNLADCFVAIFTNPAEFDASGR 157
            :..:|...|.:.|:..| ..:..:|.||||||||:|||..|.|....|.|..:|||||.||:|||
Mouse    69 VTSLPFTSGMIELLSFLRMNKDRFDCIIISDSNSIFIDWVLEAAAFHDVFDHVFTNPASFDSSGR 133

  Fly   158 LMVRAHHQQSDCKLSASNLCKGRVLEHFVIEQDLRRSIRYDHVFYVGDGNNDICPVLRQRACDFA 222
            |.|:.:|..| |.....||||..||..| |::.|::.:||..:.|:|||.||:|||...:..|.|
Mouse   134 LTVKNYHAHS-CTRCPKNLCKNTVLGEF-IDKQLQKGVRYTRIVYIGDGGNDVCPVTFLKKNDVA 196

  Fly   223 CARKGFAMEKHLLRNRSKLK-LRAQLLIWKSGFDLMDQM 260
            ..|:|:.:.:.|.:....|: :.:.:::|.||.:::..:
Mouse   197 MPREGYTLHRTLAKMSQNLEPMESSIVVWSSGVEIISHL 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12237	NP_608336.1	Put_Phosphatase	30..264	CDD:284339	82/233 (35%)
Phospho2	NP_082797.1	Put_Phosphatase	3..239	CDD:284339	83/234 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834896
Domainoid	1	1.000	164	1.000	Domainoid score	I3927
eggNOG	1	0.900	-	-		E1_KOG3120
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41756
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4192
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57813
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002454
OrthoInspector	1	1.000	-	-		otm43499
orthoMCL	1	0.900	-	-		OOG6_103740
Panther	1	1.100	-	-	LDO	PTHR20889
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5703
SonicParanoid	1	1.000	-	-		X1634
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790