DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12237 and Phospho1

DIOPT Version :9

Sequence 1:	NP_608336.1	Gene:	CG12237 / 32967	FlyBaseID:	FBgn0031048	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001099303.1	Gene:	Phospho1 / 287644	RGDID:	1306182	Length:	289	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	85/272 - (31%)
Similarity:	137/272 - (50%)	Gaps:	20/272 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PAAVAAAVASCRLRK-QQRRRLAA---------FDFDHTIVSQNTDTVVRDLLPTEVTSAKVNEL 63
            |..::.|.:||.... .|..|:||         ||||.|||.:|:|..:....|.:.....:...
  Rat    20 PRRLSLAPSSCSSSPCSQDGRMAAPGAPRFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRAT 84

  Fly    64 VENDCWTEYMAEVFRLLHEQQVSEARIRDTIRGIPEVPGFVRLIKHLAKR-LHYDLIIISDSNSV 127
            .....:.|||..||:.|.||.|....:|.....||..||...|::.:||: ..:::|:|||:|:.
  Rat    85 YREGYYNEYMQRVFKYLGEQGVRPRDLRAVYETIPLSPGMGDLLQFIAKQGSCFEVILISDANTF 149

  Fly   128 FIDEWLRAHNLADCFVAIFTNPAEFDASGRLMVRAHHQQSDCKLSASNLCKGRVLEHFVIEQDLR 192
            .::..|||......|..|.:||:..||.|.|.:|..|..| |....:|:||.:||..::.|: .|
  Rat   150 GVESALRAAGHHSLFRRILSNPSGPDARGLLTLRPFHTHS-CSRCPANMCKHKVLSEYLRER-AR 212

  Fly   193 RSIRYDHVFYVGDGNNDICPVLRQRACDFACARKGFAMEKHLLRNRSKLK---LRAQLLIWKSGF 254
            ..:.::.:||||||.||.||:......|.|..|:|:.|.: |::...|.:   .||.::.|::..
  Rat   213 DGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHR-LIQEAQKAEPSSFRAHVVPWETAA 276

  Fly   255 DL---MDQMLAL 263
            |:   :.|:|.:
  Rat   277 DVRQHLQQVLKM 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12237	NP_608336.1	Put_Phosphatase	30..264	CDD:284339	79/250 (32%)
Phospho1	NP_001099303.1	Put_Phosphatase	49..286	CDD:284339	76/239 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338481
Domainoid	1	1.000	163	1.000	Domainoid score	I3874
eggNOG	1	0.900	-	-		E1_KOG3120
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4089
OMA	1	1.010	-	-		QHG57813
OrthoDB	1	1.010	-	-		D1454608at2759
OrthoFinder	1	1.000	-	-		FOG0002454
OrthoInspector	1	1.000	-	-		otm45562
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR20889
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1634
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870