DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12237 and Phospho1

DIOPT Version :9

Sequence 1:	NP_608336.1	Gene:	CG12237 / 32967	FlyBaseID:	FBgn0031048	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_694744.1	Gene:	Phospho1 / 237928	MGIID:	2447348	Length:	267	Species:	Mus musculus

Alignment Length:	244	Identity:	79/244 - (32%)
Similarity:	127/244 - (52%)	Gaps:	10/244 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RRLAAFDFDHTIVSQNTDTVVRDLLPTEVTSAKVNELVENDCWTEYMAEVFRLLHEQQVSEARIR 91
            |.|..||||.|||.:|:|..:....|.:.....:........:.|||..||:.|.||.|....:|
Mouse    26 RFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRATYREGYYNEYMQRVFKYLGEQGVRPRDLR 90

  Fly    92 DTIRGIPEVPGFVRLIKHLAKR-LHYDLIIISDSNSVFIDEWLRAHNLADCFVAIFTNPAEFDAS 155
            .....||..||...|::.:||: ..:::|:|||:|:..::..|||......|..|.:||:..||.
Mouse    91 AVYETIPLSPGMGDLLQFIAKQGSCFEVILISDANTFGVESALRAAGHHSLFRRILSNPSGPDAR 155

  Fly   156 GRLMVRAHHQQSDCKLSASNLCKGRVLEHFVIEQDLRRSIRYDHVFYVGDGNNDICPVLRQRACD 220
            |.|.:|..|..| |....:|:||.:||..::.|: .|..:.::.:||||||.||.||:......|
Mouse   156 GLLTLRPFHTHS-CSRCPANMCKHKVLSEYLRER-ARDGVHFERLFYVGDGANDFCPMGLLAGGD 218

  Fly   221 FACARKGFAMEKHLLRNRSKLK---LRAQLLIWKSGFDL---MDQMLAL 263
            .|..|:|:.|.: |::...|.:   .||.::.|::..|:   :.|:|.:
Mouse   219 VAFPRRGYPMHR-LIQEAQKAEPSSFRAHVVPWETAADVRQHLQQVLKM 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12237	NP_608336.1	Put_Phosphatase	30..264	CDD:284339	77/241 (32%)
Phospho1	NP_694744.1	Put_Phosphatase	27..264	CDD:284339	77/239 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834898
Domainoid	1	1.000	164	1.000	Domainoid score	I3927
eggNOG	1	0.900	-	-		E1_KOG3120
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4192
Isobase	1	0.950	-	0	Normalized mean entropy	S7266
OMA	1	1.010	-	-		QHG57813
OrthoDB	1	1.010	-	-		D1454608at2759
OrthoFinder	1	1.000	-	-		FOG0002454
OrthoInspector	1	1.000	-	-		otm43499
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR20889
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1634
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.820