DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcd-1 and cnot9

DIOPT Version :9

Sequence 1:	NP_608335.1	Gene:	Rcd-1 / 32966	FlyBaseID:	FBgn0031047	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_999925.1	Gene:	cnot9 / 406632	ZFINID:	ZDB-GENE-030131-1558	Length:	298	Species:	Danio rerio

Alignment Length:	282	Identity:	221/282 - (78%)
Similarity:	249/282 - (88%)	Gaps:	3/282 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QTEQEKVYQWINELAHPDTRETALLELSKKRE--TDLAPMLWNSFGTACALLQEIVNIYPSITPP 85
            |.::||:|||||||:.|:|||.||||||||||  ||||||||:|.||..|||||||||||||.||
Zfish    15 QVDREKIYQWINELSSPETRENALLELSKKRESVTDLAPMLWHSCGTIAALLQEIVNIYPSINPP 79

  Fly    86 TLTAHQSNRVCNALALLQCVASHPETRTAFLQAQIPLYLYPFLSTTSKTRPFEYLRLTSLGVIGA 150
            |||||||||||||||||||||||.|||:|||.|.|||:|||||.|.|||||||||||||||||||
Zfish    80 TLTAHQSNRVCNALALLQCVASHVETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGA 144

  Fly   151 LVKTDEQEVITFLLTTEIVPLCLSIMDSGSELSKTVATFIIQKILLDESGLSYICQTYERFSHVA 215
            ||||||||||.|||||||:||||.||:|||||||||||||:||||||::||:|||||||||||||
Zfish   145 LVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVA 209

  Fly   216 ITLGKMVIQLAKDPCARLLKHVVRCYLRLSDNTRARKALGQCLPDQLRDGTFALCLQEDKSTKQW 280
            :.|||||:||:|:|.|||||||||||||||||:|||:||.|||||||:|.|||..|::|.:||:|
Zfish   210 MILGKMVLQLSKEPSARLLKHVVRCYLRLSDNSRAREALRQCLPDQLKDTTFAQVLKDDSTTKRW 274

  Fly   281 LQMLLKNLELGATPQQIGMSPL 302
            |..|:|||:.|......|: ||
Zfish   275 LAQLVKNLQEGQVTDPRGI-PL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcd-1	NP_608335.1	Rcd1	40..288	CDD:281998	204/249 (82%)
cnot9	NP_999925.1	Rcd1	32..282	CDD:281998	204/249 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592272
Domainoid	1	1.000	422	1.000	Domainoid score	I606
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3973
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1652
OMA	1	1.010	-	-		QHG53719
OrthoDB	1	1.010	-	-		D1129961at2759
OrthoFinder	1	1.000	-	-		FOG0003765
OrthoInspector	1	1.000	-	-		oto39418
orthoMCL	1	0.900	-	-		OOG6_102178
Panther	1	1.100	-	-	LDO	PTHR12262
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1073
SonicParanoid	1	1.000	-	-		X2622
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940