DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment e(y)3 and DPF1

DIOPT Version :9

Sequence 1:	NP_001259719.1	Gene:	e(y)3 / 32965	FlyBaseID:	FBgn0087008	Length:	2012	Species:	Drosophila melanogaster
Sequence 2:	XP_011525658.1	Gene:	DPF1 / 8193	HGNCID:	20225	Length:	407	Species:	Homo sapiens

Alignment Length:	111	Identity:	42/111 - (37%)
Similarity:	54/111 - (48%)	Gaps:	14/111 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1701 CGVCLRSQHRNARDMPEAFIRCYTCRKRVHPSCVDMPPRMVGRVRNYNWQCAGCKCCIKCRSSQR 1765
            |..||....:..  .||..|.|..|.:..||||:.....|...||.|.|||..||.|..|.:|:.
Human   284 CDFCLGGSKKTG--CPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSEN 346

  Fly  1766 PG----------KMLYCEQCDRGYHIYCLG--LRTVPDGRWSCERC 1799
            .|          ::|:|:.||||||:|||.  :...|:|.|||..|
Human   347 DGASWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLC 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	19/52 (37%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	7/23 (30%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	11/35 (31%)
		PHD2_PHF10	1756..1799	CDD:277004	20/54 (37%)
DPF1	XP_011525658.1	Requiem_N	39..105	CDD:404861
		SFP1	<212..246	CDD:227516
		PHD1_DPF1	279..336	CDD:277160	19/53 (36%)
		PHD2_d4	337..392	CDD:277005	20/54 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2732
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.960