Protein Alignment e(y)3 and phf10

DIOPT Version :9

• Sequence 1: NP_001259719.1
• Gene: e(y)3 / 32965
• FlyBaseID: FBgn0087008
• Length: 2012
• Species: Drosophila melanogaster
• Sequence 2: NP_956949.3
• Gene: phf10 / 393628
• ZFINID: ZDB-GENE-040426-1573
• Length: 490
• Species: Danio rerio
• Alignment Length: 588
• Identity: 159/588 - (27%)
• Similarity: 263/588 - (44%)
• Gaps: 159/588 - (27%)

  Fly  1253 MASLMEP------PLTPQKQPDFLNNEESQSSMVSNVSMMDSNQGQSADAILGSALKRPKKKKM- 1310
            ||:::.|      |.||..|                 |:.|..:..|:|   ||  :.||:::|
Zfish     1 MAAVLSPRPCDSNPATPGTQ-----------------SIKDDIEENSSD---GS--QAPKRRRMG 43

  Fly  1311 --------ETCVAE--DTDYSASSIAEYDWPPPKGCCPSKNRDT---FMIQEQVALYLGITSFKR 1362
                    :|...|  .|.:.|.::.||.|||.         ||   :|:||||:.|||:|||||
Zfish    44 SGDSSRSCDTSTHELGPTYFPAENLTEYKWPPD---------DTGEYYMLQEQVSEYLGVTSFKR 99

  Fly  1363 KYPDLPRRSVDMEERNWLQEKGLVSEKLCDLGITAVWASDILDIMYADFFDKYEEYKEYIRRKHL 1427
            |||::.||.:..:|:.:|:|:.:::|..|.||:||:.:.:::|:|..::..|:.||...::.:..
Zfish   100 KYPEMERRDLSHKEKLYLREQNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQERER 164

  Fly  1428 REIEAKQKALGLT----------VGAGRGLQARDRAMLSATKWNAYFNKSRKDERQSCMDLQTFT 1482
            :.|..:.....|:          |.|.:..:...:|...|.::|:.||:.|.:||::..||||..
Zfish   165 QRITKEYNVSTLSVQMQQQNPQKVEASKVPEYIKKAAKKAAEFNSNFNRERMEERRAYFDLQTHI 229

  Fly  1483 INQPQPRTAPTCTRLERSTSDLIRAVAEEANIPAPPNLLPPRDYDEAFRNSDYAYPLTVVPDQFS 1547
            |..||.:.                            .:|||.      |.....:|:.::|.||.
Zfish   230 IQVPQGKY----------------------------KILPPE------RTKTGPFPVALIPGQFQ 260

  Fly  1548 MAYRQFEPAELRAYPLDTALDKPPTDLMAQLLQAKSEAVGSDEIKTSAPAPKDLGQEQSAIKSVT 1612
            ..|:::.|.|||..||:|||.:||.|.....|.:..::...|:           |:|..
Zfish   261 EYYKRYSPNELRYLPLNTALFEPPLDPELPALDSDGDSDDGDD-----------GKEDG------ 308

  Fly  1613 VTAPVRRSRRSTRQQTDKVRTASSSSTSSAQSVSSASSGNGSSSDTESGDESDFSSTSSCSSSTG 1677
                 ::::.|                      |.:||||     |..||..|    |...|...
Zfish   309 -----KKNKGS----------------------SDSSSGN-----TSDGDSQD----SGIHSKVK 337

  Fly  1678 ASSGAGSEDEDGNECS-----------SSVRLSTCGVCLRSQHRNARDMPEAFIRCYTCRKRVHP 1731
            :....|::.:||...|           ..:..:.||:|.:.:..|.|..|||.|.|..|:...||
Zfish   338 SKDRPGAQSKDGTPRSIQHKSVPGYKPKVIPNAICGICQKGKEANKRGKPEALIHCSQCQNSGHP 402

  Fly  1732 SCVDMPPRMVGRVRNYNWQCAGCKCCIKCRSSQRPGKMLYCEQCDRGYHIYCLGLRTVPDGRWSC 1796
            ||:||...:|.:::.|.|||..||.|..|:......:|::|::||||:|.:|:|:.::|.|.|.|
Zfish   403 SCLDMSVDLVAKIKMYPWQCMECKTCTVCQQPHHEEEMMFCDKCDRGFHTFCVGMDSIPMGCWVC 467

  Fly  1797 ERC 1799
            :.|
Zfish   468 DLC 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	22/53 (42%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	10/24 (42%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	9/25 (36%)
		PHD2_PHF10	1756..1799	CDD:277004	15/42 (36%)
phf10	NP_956949.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..61		18/81 (22%)
		SAY	83..292		72/242 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..362		22/130 (17%)
		PHD1_PHF10	371..425	CDD:277003	22/53 (42%)
		PHD2_PHF10	427..470	CDD:277004	15/42 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1512
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	1	1.000	-	-		FOG0007125
OrthoInspector	1	1.000	-	-		oto38847
orthoMCL	1	0.900	-	-		OOG6_107234
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6219
SonicParanoid	1	1.000	-	-		X5215
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.640