DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment e(y)3 and Dpf2

DIOPT Version :9

Sequence 1:	NP_001259719.1	Gene:	e(y)3 / 32965	FlyBaseID:	FBgn0087008	Length:	2012	Species:	Drosophila melanogaster
Sequence 2:	XP_006230912.1	Gene:	Dpf2 / 361711	RGDID:	1311699	Length:	405	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	89/320 - (27%)
Similarity:	134/320 - (41%)	Gaps:	48/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1512 ANIPAPPNLLPPR---DYDEAFRNSDYAYPLTVVPDQFSM-AYRQFEPAELRAYPLDTALDK--- 1569
            |:.|..|.|..|.   |.|:..:...     .:..|..|: |..:.:|.|.|..| |..:|.
  Rat    85 AHPPEDPRLSFPSIKPDTDQTLKKEG-----LISQDGSSLEALLRTDPLEKRGAP-DPRVDDDSL 143

  Fly  1570 ---PPTDLMA--QLLQAKSEAVGSDEIKTSAPAPKDLGQEQSAIKSVTVTAPVRRSRRSTRQQTD 1629
               |.|:..|  ::|:........|:.......||..|:.:|  ||..|::..::...|..:..|
  Rat   144 GEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKS--KSKGVSSARKKLDASILEDRD 206

  Fly  1630 KVRTASSS----STSSA-QSVSSASSGN--GSS--------SDTESGDESDFSSTSSCSSSTGAS 1679
            |.....:|    .||.| |.|......|  |.|        ::.|..|:.|....:..|..
  Rat   207 KPYACDNSFKQKHTSKAPQRVCGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQR---- 267

  Fly  1680 SGAGSEDEDGNECSSSVRL--STCGVCLRSQHRNAR-DMPEAFIRCYTCRKRVHPSCVDMPPRMV 1741
                ||::...:....:.|  :.|..||.....|.: ..||..:.|..|.:..||||:...|.|:
  Rat   268 ----SEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMM 328

  Fly  1742 GRVRNYNWQCAGCKCCIKCRSSQRPGKMLYCEQCDRGYHIYCL--GLRTVPDGRWSCERC 1799
            ..|:.|.|||..||||..|.:|:...::|:|:.||||||:|||  .:...|:|.|||..|
  Rat   329 AAVKTYRWQCIECKCCNLCGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	19/54 (35%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	7/25 (28%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	11/25 (44%)
		PHD2_PHF10	1756..1799	CDD:277004	20/44 (45%)
Dpf2	XP_006230912.1	Requiem_N	13..75	CDD:404861
		SFP1	<201..247	CDD:227516	11/45 (24%)
		PHD1_DPF2_like	286..341	CDD:277161	19/54 (35%)
		PHD2_d4	343..388	CDD:277005	20/44 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10615
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110