Protein Alignment e(y)3 and Kat6a

DIOPT Version :9

• Sequence 1: NP_001259719.1
• Gene: e(y)3 / 32965
• FlyBaseID: FBgn0087008
• Length: 2012
• Species: Drosophila melanogaster
• Sequence 2: NP_001094040.1
• Gene: Kat6a / 306571
• RGDID: 1304892
• Length: 1998
• Species: Rattus norvegicus
• Identity: / - (0%)
• Similarity: / - (0%)
• Gaps: / - (0%)

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600
		RanBP2-type Zn finger	1700..1725	CDD:275375
		RanBP2-type Zn finger	1749..1775	CDD:275375
		PHD2_PHF10	1756..1799	CDD:277004
Kat6a	NP_001094040.1	Required for activation of RUNX1-1. /evidence=ECO:0000250|UniProtKB:Q92794	1..144
		Required for nuclear localization. /evidence=ECO:0000250	52..166
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..93
		H15	85..162	CDD:197772
		Interaction with PML. /evidence=ECO:0000250	144..662
		PHD1_MOZ_MORF	205..262	CDD:277090
		PHD2_KAT6A_6B	264..310	CDD:277002
		Interaction with RUNX1-1. /evidence=ECO:0000250	312..662
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	336..377
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	440..464
		Catalytic. /evidence=ECO:0000250	486..776
		PLN00104	<502..776	CDD:215056
		Mediates interaction with BRPF1, required for histone H3 acetyltransferase activity. /evidence=ECO:0000250	505..808
		Acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:Q92794	643..647
		Acetyl-CoA binding. /evidence=ECO:0000250|UniProtKB:Q92794	652..658
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	783..947
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	982..1079
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1096..1175
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1195..1436
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1450..1567
		Interaction with PML. /evidence=ECO:0000250	1510..1735
		Interaction with RUNX1-2. /evidence=ECO:0000250	1510..1635
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1630..1702
		Required for activation of RUNX1-2. /evidence=ECO:0000250	1907..1942

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000