DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment e(y)3 and Dpf2

DIOPT Version :9

Sequence 1:	NP_001259719.1	Gene:	e(y)3 / 32965	FlyBaseID:	FBgn0087008	Length:	2012	Species:	Drosophila melanogaster
Sequence 2:	NP_001278007.1	Gene:	Dpf2 / 19708	MGIID:	109529	Length:	405	Species:	Mus musculus

Alignment Length:	330	Identity:	88/330 - (26%)
Similarity:	130/330 - (39%)	Gaps:	68/330 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1512 ANIPAPPNLLPPR---DYDEAFRNSDYAYPLTVVPDQFSM-AYRQFEPAELRAYPLDTALDK--- 1569
            |:.|..|.|..|.   |.|:..:...     .:..|..|: |..:.:|.|.|..| |..:|.
Mouse    85 AHPPEDPRLSFPSIKPDTDQTLKKEG-----LISQDGSSLEALLRTDPLEKRGAP-DPRVDDDSL 143

  Fly  1570 ---------------PPTDLMAQLLQAKSEAVGSDEIKTSAPAPKDLGQEQSAIKSVTVTAPVRR 1619
                           .|.|.:..|          |:.......||..|:.:|  ||..|::..::
Mouse   144 GEFPVSNSRARKRIIEPDDFLDDL----------DDEDYEEDTPKRRGKGKS--KSKGVSSARKK 196

  Fly  1620 SRRSTRQQTDKVRTASSS----STSSA-QSVSSASSGN--GSS--------SDTESGDESDFSST 1669
            ...|..:..||.....:|    .||.| |.|......|  |.|        ::.|..|:.|....
Mouse   197 LDASILEDRDKPYACDNSFKQKHTSKAPQRVCGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSRPP 261

  Fly  1670 SSCSSSTGASSGAGSEDEDGNECSSSVRL--STCGVCLRSQHRNAR-DMPEAFIRCYTCRKRVHP 1731
            :..|..        ||::...:....:.|  :.|..||.....|.: ..||..:.|..|.:..||
Mouse   262 TPVSQR--------SEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHP 318

  Fly  1732 SCVDMPPRMVGRVRNYNWQCAGCKCCIKCRSSQRPGKMLYCEQCDRGYHIYCL--GLRTVPDGRW 1794
            ||:...|.|:..|:.|.|||..||||..|.:|:...::|:|:.||||||:|||  .:...|:|.|
Mouse   319 SCLQFTPVMMAAVKTYRWQCIECKCCNLCGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSW 383

  Fly  1795 SCERC 1799
            ||..|
Mouse   384 SCHLC 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	19/54 (35%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	7/25 (28%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	11/25 (44%)
		PHD2_PHF10	1756..1799	CDD:277004	20/44 (45%)
Dpf2	NP_001278007.1	Requiem_N	13..79	CDD:290758
		PHD1_DPF2_like	286..341	CDD:277161	19/54 (35%)
		PHD2_d4	343..388	CDD:277005	20/44 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10615
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110