DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment e(y)3 and dpf3

DIOPT Version :9

Sequence 1:	NP_001259719.1	Gene:	e(y)3 / 32965	FlyBaseID:	FBgn0087008	Length:	2012	Species:	Drosophila melanogaster
Sequence 2:	XP_012823348.1	Gene:	dpf3 / 100125167	XenbaseID:	XB-GENE-6067294	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	75/308 - (24%)
Similarity:	114/308 - (37%)	Gaps:	63/308 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1555 PAELRAYPLDTALDK----PPTDLMAQLLQAKSEA---VGSDEIKTSAPA-----------PKDL 1601
            |.:|..||......|    ||.|...:||:.||:.   :..|.:......           .||:
Frog    68 PGQLYTYPARCWRKKRRLHPPEDPRLRLLEIKSDVDFPLRKDNVLAEGTTLEALLRGEGIEKKDV 132

  Fly  1602 GQEQSAIK------------------SVTVTAPVRRSRRSTRQQTDKVRTASSSSTSSAQSV--- 1645
            ..|:|..:                  .:....|.|::|...|.:..:.|..:|........|
Frog   133 RDEESLQEIQRVLENDENADDANGEDDIEEEVPKRKNRSRGRARGGRRRNDTSLDEHDKPYVCDN 197

  Fly  1646 SSASSGNGSSSD-------------------TESGDESDFSSTSSCSSSTGASSGAGSEDEDGNE 1691
            |.....|..::|                   |...||.........:.|..:.|...:|::...:
Frog   198 SYKQKHNSKTADKVCGKRYKNRPGLSYHYAHTHLADEEGTDCRDQDTRSPSSPSAIRNENQKPRK 262

  Fly  1692 CSSSVRLST--CGVCLRSQHRNARD-MPEAFIRCYTCRKRVHPSCVDMPPRMVGRVRNYNWQCAG 1753
            .:....||.  |..||.....|.:. .||..:.|..|.:..||:|:.....|...|:.|.|||..
Frog   263 GTDGAILSNNYCDFCLGDSSINKKSGQPEELVSCADCGRSGHPTCLQFTVNMTEAVKTYQWQCIE 327

  Fly  1754 CKCCIKCRSSQRPGKMLYCEQCDRGYHIYCL--GLRTVPDGRWSCERC 1799
            ||.||.|.:|:...::|:|:.||||||:|||  .:...|:|.|||..|
Frog   328 CKSCIVCGTSENDEQLLFCDDCDRGYHMYCLIPPMAEPPEGSWSCHLC 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)3	NP_001259719.1	PHD_SF	1700..1754	CDD:304600	17/56 (30%)
		RanBP2-type Zn finger	1700..1725	CDD:275375	7/27 (26%)
		RanBP2-type Zn finger	1749..1775	CDD:275375	11/25 (44%)
		PHD2_PHF10	1756..1799	CDD:277004	20/44 (45%)
dpf3	XP_012823348.1	Requiem_N	13..84	CDD:290758	5/15 (33%)
		PHD1_DPF3	273..329	CDD:277162	17/55 (31%)
		PHD2_d4	330..375	CDD:277005	20/44 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312433at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10615
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110