Protein Alignment CG14212 and PHOSPHO1

DIOPT Version :10

• Sequence 1: NP_608333.1
• Gene: CG14212 / 32964
• FlyBaseID: FBgn0031045
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_047291460.1
• Gene: PHOSPHO1 / 162466
• HGNCID: 16815
• Length: 350
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 84/283 - (29%)
• Similarity: 130/283 - (45%)
• Gaps: 46/283 - (16%)

  Fly     3 AISRSLRLSRCLSPFGRGLSASSSPGPRTLVAIDFDRTIVEQDS-----YLAVSQLLPTSQRKEL 62
            :::.|...|.|..|..:....::...||.|:..|||.|||:::|     ..|..|.||.|.|...
Human    82 SLAPSSSSSCCSPPCSQDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATY 146

  Fly    63 QDQIPKCGWLSFISQVLQRLH---GEHKVNSASVGKRVRSLTAV-------PGMLRVMRQLARIP 117
            ::        .|.::.:||:.   ||.       |.|.|.|:|:       |||..:::.:|:..
Human   147 RE--------GFYNEYMQRVFKYLGEQ-------GVRPRDLSAIYEAIPLSPGMSDLLQFVAKQG 196

  Fly   118 E-LELCIVSDANSFFIGEWLQAYAIECLFAGGVFTNPACVQASGELLVLPYQEQTDCDLCPSNMC 181
            . .|:.::||||:|.:...|:|.....||. .:.:||:...|.|.|.:.|:...: |..||:|||
Human   197 ACFEVILISDANTFGVESSLRAAGHHSLFR-RILSNPSGPDARGLLALRPFHTHS-CARCPANMC 259

  Fly   182 KGSVMD----ELTCSG-RYERLIYVGDSCNDLCAIKRLRQKDVACIRRGFELH----GKMTAHGQ 237
            |..|:.    |....| .:|||.||||..||.|.:..|...|||..|||:.:|    ....|...
Human   260 KHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPS 324

  Fly   238 ELACSVLTWRDGHE----LEELL 256
            ....||:.|....:    |:::|
Human   325 SFRASVVPWETAADVRLHLQQVL 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14212	NP_608333.1	Haloacid Dehalogenase-like Hydrolases	31..260	CDD:473868	78/255 (31%)
PHOSPHO1	XP_047291460.1	Put_Phosphatase	110..347	CDD:284339	77/253 (30%)