Protein Alignment MKP-4 and Dusp18

DIOPT Version :10

• Sequence 1: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_776106.1
• Gene: Dusp18 / 75219
• MGIID: 1922469
• Length: 188
• Species: Mus musculus
• Alignment Length: 137
• Identity: 43/137 - (31%)
• Similarity: 71/137 - (51%)
• Gaps: 7/137 - (5%)

  Fly    39 IDEVDTGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHILEASFLTTKYIQ--IADMPREDI 101
            :.::...||:.|..||.:...|.|.:||.::.: ||.:.....|    ..:|:|  :.|.|...:
Mouse    20 LSQITKSLFISNGVAANNKLLLSSNQITTVINV-SVEVANTFYE----DIQYVQVPVVDAPVARL 79

  Fly   102 LQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPN 166
            ....:...|.|.|...|:|..|:||..|||||::..:||:||.|.:..:.|:...|:.|..::||
Mouse    80 SNFFDSVADRIHSVEMQKGRTLLHCAAGVSRSAALCLAYLMKYHAMSLVDAHTWTKSCRPIIRPN 144

  Fly   167 AGFVSQL 173
            :||..||
Mouse   145 SGFWEQL 151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	43/137 (31%)
Dusp18	NP_776106.1	PTP_DSP_cys	19..176	CDD:475123	43/137 (31%)
		Sufficient for mitochondrial localization	95..141		18/45 (40%)