Protein Alignment MKP-4 and Mkp3

DIOPT Version :10

• Sequence 1: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 81/295 - (27%)
• Similarity: 116/295 - (39%)
• Gaps: 60/295 - (20%)

  Fly     4 SQSQRQAWPSSSAGGGKAQDSG----VLTREDFDGGPVSIDEVDTGLFLGNLTAATHMETLRSFK 64
            |.:|..:..||||.....:.|.    ..:..:::..||.|  :...|||||.|.:...|.|:.:.
  Fly   179 STTQSDSACSSSAESSDCESSSHHHHHHSHHNYNEAPVEI--IPGLLFLGNATHSCDSEALKKYN 241

  Fly    65 ITHILTLDSVPLPQHILEASFLTTKYIQ--IADMPREDILQHLEGCVDFISSALAQQGNVLVHCY 127
            |.::|.: :..||....|:..:  ||:|  |.|...:|:..|....:.||..|.:....|||||.
  Fly   242 IKYVLNV-TPDLPNKFKESGDI--KYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHCL 303

  Fly   128 FGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFR---------RMGCKI 183
            .|||||.:..:||:|....|....|:.:|:.::..|.||..|:.||..|.         |..|..
  Fly   304 AGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQLRLRPGSRFSCSC 368

  Fly   184 ---DPNCQR----YKIHRLRLAGEQMRKAKILPQSFHSVVRPDPDI--TRENPEPIVFRCRRCRR 239
               |.||.:    ...|.....|                |.||..|  .|..|.....:..:.
  Fly   369 IAPDCNCMQTTGFMATHLANATG----------------VSPDSGIEFDRWTPSDTGLKXEQS-- 415

  Fly   240 VLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLP 274
              ..||.||       ||.:.||    ..|||..|
  Fly   416 --GGKSFVL-------PPSQEVP----FAAAATSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	46/137 (34%)
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723
		DSP_MKP_classII	215..352	CDD:350414	48/141 (34%)