Protein Alignment MKP-4 and Dusp16

DIOPT Version :10

• Sequence 1: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001100094.1
• Gene: Dusp16 / 297682
• RGDID: 1310721
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 93/381 - (24%)
• Similarity: 132/381 - (34%)
• Gaps: 139/381 - (36%)

  Fly    46 LFLGNLTAATHMETLRSFKITHILTL-DSVPLPQHILEASFLTTKYIQIADMPREDILQHLEGCV 109
            |:||......:.|.::...|.::|.. ::.|.|..|.|:.||.   :.:.|...|.||..|:..|
  Rat   166 LYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLR---VPVNDSFCEKILPWLDKSV 227

  Fly   110 DFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFV---- 170
            |||..|.|..|.||:||..|:|||::..|||:|||.::....||..||.||..:.||..|:
  Rat   228 DFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMGQLM 292

  Fly   171 ----------------SQLKLF----------------RRMGCKIDPNC---------QRYKIH- 193
                            |:|||.                |:....:.|.|         ||. :|
  Rat   293 DYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRL-VHP 356

  Fly   194 ---------------------RLRLAGEQMRKAKILPQSF-----------------HSVVRPD- 219
                                 .|:|:.|::..:..|.:||                 |.....|
  Rat   357 ASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSEDA 421

  Fly   220 -----PDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQ--- 276
                 |..|.:....:      |:  .:....|.|..|...|       :|||   |.:|.|
  Rat   422 MEYYKPSATLDGTSKL------CQ--FSPVQEVSEQTPETSP-------DKEE---AHIPRQPQA 468

  Fly   277 ---SHDQAENHHGARMLEQLSERIRQSSLG-------SPGHES---TPNYCRSILF 319
               |..|....|.          :|.||.|       ||.|.|   ..||..:.||
  Rat   469 TRPSESQTTRLHS----------VRTSSTGSTQRPFFSPLHRSGSVEDNYHTNFLF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	49/149 (33%)
Dusp16	NP_001100094.1	DSP_MapKP	10..136	CDD:238723
		PTP_DSP_cys	158..301	CDD:475123	47/137 (34%)