DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MKP-4 and Epm2a

DIOPT Version :10

Sequence 1:NP_608332.2 Gene:MKP-4 / 32963 FlyBaseID:FBgn0031044 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001263691.1 Gene:Epm2a / 114005 RGDID:71047 Length:331 Species:Rattus norvegicus


Alignment Length:107 Identity:27/107 - (25%)
Similarity:43/107 - (40%) Gaps:24/107 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 DMPREDILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYEL---- 155
            ||..|..:|.|...|..:.:.|.....|.|||..||.||::.|..:      |.::..:.|    
  Rat   235 DMSTEGRVQMLPQAVCLLHALLENGHTVYVHCNAGVGRSTAAVCGW------LHYVIGWSLRKVQ 293

  Fly   156 --VKAKRR--FVQPNAGFVSQLKLFRRMGCKIDPNCQRYKIH 193
              :.|||.  ::...|...:|...|::.|          |:|
  Rat   294 YFIMAKRPAVYIDEEALAQAQQDFFQKFG----------KVH 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MKP-4NP_608332.2 DSP 39..175 CDD:350348 23/87 (26%)
Epm2aNP_001263691.1 CBM20_laforin 1..129 CDD:99881
DSP_laforin-like 155..312 CDD:350375 22/82 (27%)
Glucan phosphatase signature motif CXAGXGR. /evidence=ECO:0000250|UniProtKB:O95278 266..272 3/5 (60%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.