DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14221 and TDX

DIOPT Version :9

Sequence 1:	NP_001259713.1	Gene:	CG14221 / 32961	FlyBaseID:	FBgn0031042	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_188415.2	Gene:	TDX / 821056	AraportID:	AT3G17880	Length:	380	Species:	Arabidopsis thaliana

Alignment Length:	365	Identity:	69/365 - (18%)
Similarity:	132/365 - (36%)	Gaps:	114/365 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 FAAENPLSPEVIEQLYDKELLMCFWK---------VDEVLGTPPTVLRQYAHEL-TKETIKPPDE 278
            |..:..|:|.:   |:|..|:  |:|         |.::..|.    |.|..:. ||.:..|..:
plant    13 FVEQLKLNPSI---LHDPSLV--FFKEYLRSLGAQVPKIEKTE----RDYEDKAETKPSFSPKHD 68

  Fly   279 FNEEEITVPPMIVPLEVTVEISDP---EPSTENSQVQPDAVHLAEIRSENVAEAEEETETEAEA- 339
            .::::|        :|..||:.:.   ||  :|...||.....||:..||..:|:.|.....||
plant    69 DDDDDI--------MESDVELDNSDVVEP--DNEPPQPMGDPTAEVTDENRDDAQSEKSKAMEAI 123

  Fly   340 --GAAPEAKTAPVAAKRTKTIRIPPIWVPSDQRTHAALIYTYFRAQTTTFL---PPDPVPEPPHI 399
              |...||     ....||.:.:.|.         :|::|.   .:.:.||   .|:......::
plant   124 SDGRFDEA-----IEHLTKAVMLNPT---------SAILYA---TRASVFLKVKKPNAAIRDANV 171

  Fly   400 VMIFDA-----YKKKDLAILLETCREDIPLYGFFNGDNPLTAQFIANSVEKYNAKPYVPTDKIVL 459
            .:.|::     ||.:.:|                   ..:..|:...:.:.:.|......::|..
plant   172 ALQFNSDSAKGYKSRGMA-------------------KAMLGQWEEAAADLHVASKLDYDEEIGT 217

  Fly   460 KVNKVNSPTIPTLMAYGPSYVSANSVVGHQEATQFFPANYKSALQEEEELHAVKTEKPKKRKKNK 524
            .:.||..              :|..:..|:...|        .|::|:||...:.|:.|:::..:
plant   218 MLKKVEP--------------NAKRIEEHRRKYQ--------RLRKEKELQRAERERRKQQEAQE 260

  Fly   525 KGGDPEESGKADAGPADAQM-----EAEEAVKTSPEEGAS 559
            :        :|.|...|.::     .:|...||...:.||
plant   261 R--------EAQAALNDGEVISIHSTSELEAKTKAAKKAS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14221	NP_001259713.1	Thioredoxin_like	11..111	CDD:294274
CG14221	NP_001259713.1	DUF4746	233..508	CDD:292550	54/298 (18%)
TDX	NP_188415.2	Hip_N	6..44	CDD:271228	8/35 (23%)
		TPR repeat	112..140	CDD:276809	9/32 (28%)
		PLN03088	117..>213	CDD:215568	19/131 (15%)
		TPR repeat	145..175	CDD:276809	5/32 (16%)
		TPR repeat	180..206	CDD:276809	4/44 (9%)
		PRK14552	<200..256	CDD:237753	13/77 (17%)
		TRX_family	292..374	CDD:239245	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0907
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1482186at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820