Protein Alignment CG14221 and Pdi

DIOPT Version :9

• Sequence 1: NP_001259713.1
• Gene: CG14221 / 32961
• FlyBaseID: FBgn0031042
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001287070.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 104/561 - (18%)
• Similarity: 193/561 - (34%)
• Gaps: 153/561 - (27%)

  Fly    14 LASDEEFEKFLQRSGLLVLDIYSEWCGPCLGMVGSLRKIKLELGGDNLQLAICKA-----GSISY 73
            :|:.:.|::.:..:..::::.|:.|||.|..:.....|...:|......:.:.|.     |.::
  Fly    31 VATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELA- 94

  Fly    74 LKRFNKKSEPTWMFVTSGKAINIMFGTDVPKLVAMITRMLQSTMAKETHLSYEITELQPIE--LE 136
             :::..:..||..|..||..:....|.....::|.:|:       |....:.::|.:...|  |:
  Fly    95 -EQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTK-------KTGPPAKDLTSVADAEQFLK 151

  Fly   137 QLEVRNKALRLAEEIELAESRRKRLEYLHSVTDCIMANLPDIGITVFGPQVNRDMFKKLSEPADP 201
            ..|:  ..:...:::|..|::          |...:||..|  ..|||...|.|:.
  Fly   152 DNEI--AIIGFFKDLESEEAK----------TFTKVANALD--SFVFGVSSNADVI--------- 193

  Fly   202 LKIQCKDRKVFTILPSDIATVNFAAENPLSPEVIEQLYDKELLMCFWKVDEVLGTPPTVLRQYAH 266
            .|.:.||..|....|.|.           ...|.|...::|.|..|.:|..:    |.:: .:.|
  Fly   194 AKYEAKDNGVVLFKPFDD-----------KKSVFEGELNEENLKKFAQVQSL----PLIV-DFNH 242

  Fly   267 ELTKE----TIKPPDEF--NEEEITVPPMIVPLE------------VTVEISDPEPSTE------ 307
            |...:    :||....|  :.|...:...:.||:            ||:. ||.|..|.
  Fly   243 ESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTIS-SDEEDHTRIFEFFG 306

  Fly   308 -NSQVQPDAVHLAEIRSENVAEAEEETETEAEAGAAPEAKTAPVAAKRTKTIRIPPIWVPSDQRT 371
             |.:..| .:.|.::..:......|..:..||                                |
  Fly   307 MNKEEVP-TIRLIKLEEDMAKYKPESDDLSAE--------------------------------T 338

  Fly   372 HAALIYTYFRAQTTTFLPPDPVPEP----PHIVMIFDAYKK----KDLAILLE-------TCRED 421
            ..|.:..:...:....|....:||.    |..|::...::.    |..::|:|       .|::.
  Fly   339 IEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQL 403

  Fly   422 IPLYG-----FFNGDNPLTAQF--IANSVEKYNAKPYVPTDKIVLKV-NKVNSPTIPTLMAYGPS 478
            .|:|.     :.:.::.:.|:.  .||.:|......: ||.|...|. |||....:...:.....
  Fly   404 APIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSF-PTIKYFRKEDNKVIDFNLDRTLDDFVK 467

  Fly   479 YVSANSVVGHQEATQFFPANYKSALQEEEELHAVKTEKPKK 519
            ::.||..|...|..:         ..||||      |.|||
  Fly   468 FLDANGEVADSEPVE---------ETEEEE------EAPKK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14221	NP_001259713.1	Thioredoxin_like	11..111	CDD:294274	18/101 (18%)
		DUF4746	233..508	CDD:292550	57/322 (18%)
Pdi	NP_001287070.1	ER_PDI_fam	27..474	CDD:273457	94/525 (18%)
		pdi_dom	33..133	CDD:273454	18/108 (17%)
		PDI_b_family	137..231	CDD:239279	26/127 (20%)
		PDI_b'_family	244..347	CDD:239280	20/136 (15%)
		PDI_a_PDI_a'_C	368..469	CDD:239293	19/101 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910