Protein Alignment CG14221 and CG18130

DIOPT Version :9

• Sequence 1: NP_001259713.1
• Gene: CG14221 / 32961
• FlyBaseID: FBgn0031042
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_572772.1
• Gene: CG18130 / 32161
• FlyBaseID: FBgn0030359
• Length: 706
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 304/657 - (46%)
• Similarity: 412/657 - (62%)
• Gaps: 82/657 - (12%)

  Fly     1 MAKKGGVQQLQADLASDEEFEKFLQRSGLLVLDIYSEWCGPCLGMVGSLRKIKLELGGDNLQLAI 65
            ||||||.||||||:.:|||.|:|::|.||||||:||||||||.|||||||||||::|||||.|||
  Fly     1 MAKKGGQQQLQADIQTDEELERFMERPGLLVLDVYSEWCGPCQGMVGSLRKIKLDVGGDNLHLAI 65

  Fly    66 CKAGSISYLKRFNKKSEPTWMFVTSGKAINIMFGTDVPKLVAMITRMLQSTMAKETHL-SYEITE 129
            ||:.:|:.||||||:|||.|:|||.|:|:|::||:||||||:::.:.|:.||.|.:.. :|.:.|
  Fly    66 CKSDTITALKRFNKRSEPIWLFVTGGRAVNLLFGSDVPKLVSLLVKELEKTMQKSSRPGTYRLDE 130

  Fly   130 LQPIELEQLEVRNKALRLAEEIELAESRRKRLEYLHSVTDCIMANLPDIGITVFGPQVNRDMFKK 194
            |||||:||..::.:|:..||..|.....:|:::||:.|||.||.|:||||:||||||||||||||
  Fly   131 LQPIEVEQQRIKMEAIERAERAEREIKHKKQIDYLNHVTDSIMENMPDIGVTVFGPQVNRDMFKK 195

  Fly   195 LSEPADPLKIQCKDRKVFTILPSDIATVNFAAENPLSPEVIEQLYDKELLMCFWKVDEVLGTPPT 259
            |:|||:.||:|||||:|..:.......||||.:||:.|:|||||..|||||||||:||.:||.|.
  Fly   196 LTEPAEALKMQCKDRRVIQVSTDQFEIVNFACKNPMPPDVIEQLDGKELLMCFWKIDESIGTVPN 260

  Fly   260 VLRQYAHELTKETIKPPDEFNEEEITVPPMIVPLEVTVEISDPEPST------------------ 306
            ||..||||||||.:.||::...||..:||:|..:::.||:...|..|
  Fly   261 VLMAYAHELTKERVAPPNDDIPEEHVIPPLITTMKLKVEVELKEGETWVEEISSEEEARLHQAKS 325

  Fly   307 --ENSQVQPDAVHLAEIRSENVAEAEEETETEA--------EAGAAP-----EAKTAPV------ 350
              :...:..:..||||..:.::...||.:|.|.        ..|..|     |.:..||
  Fly   326 KAKTKSISHEEAHLAEEEAADLDAEEEASEEETVMPEPGGDAMGGLPSMPGFELEIEPVDEAGED 390

  Fly   351 --------------AAKRTKTIRIPPIWVPSDQRTHAALIYTYFRAQTTTFLPPDPVPEPPHIVM 401
                          ...||||:::||||||:.:||||||||.:||.||:.||||||.|||||::|
  Fly   391 EEEVQEIKEEEPSKPLTRTKTVKMPPIWVPNSRRTHAALIYVFFRGQTSGFLPPDPKPEPPHVIM 455

  Fly   402 IFDAYKKKDLAILLETCREDIPLYGFFNGDNPLTAQFIANSVEKYNAKPYVPTDKIVLKVNKVNS 466
            .|||.|:|::..:::..::|:||||||:...|..|:.||.|.:||.:.|:...||||||||||.|
  Fly   456 AFDASKRKEIMHVIDRHKDDVPLYGFFSSAEPDEAELIATSTDKYESSPHSSGDKIVLKVNKVQS 520

  Fly   467 PTIPTLMAYGPSYVSANSVVGHQEATQFFPANYKSALQEEEELHAVKTEKPKKRKKNKKGGDPEE 531
            ..:.:|::|||||||.|..||..||.:|||.:||.  |||     |..|..||:||:|:..:..:
  Fly   521 NMMLSLVSYGPSYVSPNVTVGKDEALKFFPEDYKP--QEE-----VVVEVEKKKKKSKRATEINQ 578

  Fly   532 SGKADA------------GPADAQMEAEEAVKTSPEEGASTTSSGE-----DSCESRP----ATA 575
            ..:|.|            .||..:.||..|...:..||.:..::.|     |:....|    ..|
  Fly   579 EMEAAAAAAAAAAAHPSEAPAPVEAEAHAAEAPAAVEGDAAPAAAEAPPAGDAAPVAPPPAEPAA 643

  Fly   576 DGANPDA 582
            :||.|:|
  Fly   644 EGAAPEA 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14221	NP_001259713.1	Thioredoxin_like	11..111	CDD:294274	69/99 (70%)
		DUF4746	233..508	CDD:292550	139/327 (43%)
CG18130	NP_572772.1	TRX_NDPK	11..112	CDD:239246	69/100 (69%)
		DUF4746	234..556	CDD:292550	136/323 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I7899
eggNOG	1	0.900	-	-		E2759_KOG0907
Homologene	1	1.000	-	-		H44242
Inparanoid	1	1.050	416	1.000	Inparanoid score	I3797
Isobase	1	0.950	-	0	Normalized mean entropy	S4604
OMA	1	1.010	-	-		QHG26490
OrthoDB	1	1.010	-	-		D1482186at2759
OrthoFinder	1	1.000	-	-		FOG0012576
OrthoInspector	1	1.000	-	-		otm24926
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46135
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3807
	12	11.930