DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14221 and Txndc2

DIOPT Version :9

Sequence 1:NP_001259713.1 Gene:CG14221 / 32961 FlyBaseID:FBgn0031042 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_001139476.1 Gene:Txndc2 / 316777 RGDID:1359251 Length:550 Species:Rattus norvegicus


Alignment Length:438 Identity:80/438 - (18%)
Similarity:145/438 - (33%) Gaps:122/438 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 MFKKLSEPADPLKIQCKDRKVFTILPSDIATVNFAAENPL-SPEVIEQLYDKELLMCFWKVDEVL 254
            ||||..:.:....::....:......||:...|....|.. |.|.::....||.::.        
  Rat     1 MFKKNQKLSKDKGLEVNSVQAGAPEESDVKLNNGGKANERGSNEFLDTAQSKEKVIA-------- 57

  Fly   255 GTPPTVLRQYAHELTKETIKPPDEFNEEEITVPPMIVPLEVTVEISDPEPSTENSQVQPDAV--- 316
                :|:....|..|:|: :||.:.:...:.....|.|...    ..|:.||:|:|::.:.:   
  Rat    58 ----SVVGNMLHMSTEES-EPPQQVSSTSMFSENTIYPKHE----GSPKSSTKNTQLKQEDISKT 113

  Fly   317 --HLAEIRSENV-------------------------AEAEE-------------------ETET 335
              :..:..|.|:                         .|||:                   |...
  Rat   114 SSYSKQTNSSNIPKSLAITTYPKQGSTLKPAANGTHDREAEKPKSSEDLIQSKKGDIFKPSEDSI 178

  Fly   336 EAEAGAAPEAKTAPVAAKRTKTIRIPPIWVPSDQRTHAALIYTYFRAQTTTFLP---PDPVPEPP 397
            :::.|..|::...|:.:|:..|.:.....:.|....                :|   .||:..  
  Rat   179 QSKKGDMPKSSEDPIQSKKDDTAKSLEDTIQSKNGD----------------MPKSSEDPIQS-- 225

  Fly   398 HIVMIFDAYKKKDLAILLETCREDIPLYGFFNGDNPLTAQFIANSVEKYNAKPYVPTDKIVLKVN 462
                     ||.|.|..||...:.      ..||.|.::..|.:   |.:..|....|.|..|..
  Rat   226 ---------KKDDTARSLEDSIQS------KKGDMPKSSDTIQS---KESETPKFLQDTIQSKGG 272

  Fly   463 KVNSPTIPTLMAYGPSYVSANSVVGHQEATQFFPANYKSALQEEEELHAVKTEKPKKRKKNKKGG 527
            |:|. .:...|....|.:........|......|.:.:.:.|.:|.    |..||.|.....|.|
  Rat   273 KINK-QVKDSMKSKESKIRKPLKDSIQSKENKIPKSSQDSAQPKEG----KIHKPLKDSLPSKEG 332

  Fly   528 DPEESGKADAGPADAQMEAEEAVKTSPEEGAST----TSSGEDSCESR 571
            |..:       |::..::|:|.:..|||:....    |.|.||:.:::
  Rat   333 DISK-------PSEDTIQAKEEITVSPEDTIQAKEEITMSPEDTIQAK 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14221NP_001259713.1 Thioredoxin_like 11..111 CDD:294274
DUF4746 233..508 CDD:292550 53/326 (16%)
Txndc2NP_001139476.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50 10/48 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..428 67/364 (18%)
22 X 15 AA approximate tandem repeat of Q-P-K-X-G-D-I-P-K-S-[PS]-E-[KE]-X-I 104..440 56/318 (18%)
PTZ00121 <151..466 CDD:173412 53/271 (20%)
TRX_family 454..547 CDD:239245
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350600
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1482186at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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