DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Birc7 and Bruce

DIOPT Version :9

Sequence 1:	NP_001156719.1	Gene:	Birc7 / 329581	MGIID:	2676458	Length:	285	Species:	Mus musculus
Sequence 2:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster

Alignment Length:	119	Identity:	40/119 - (33%)
Similarity:	54/119 - (45%)	Gaps:	25/119 - (21%)

- Green bases have known domain annotations that are detailed below.

Mouse    90 MDSEDLRLASFYDWP--STAGIQPEPLAAAGFFH---TGQQDKVRCFFCYGGLQSWERGDDPWTE 149
            |.||.:|..:|..||  ......|:.:|.|||:|   :..:|:..||.|...|..||:.|:||:|
  Fly   245 MHSEAVRRQTFEKWPHMDYKWALPDQMAQAGFYHQPSSSGEDRAMCFTCSVCLVCWEKTDEPWSE 309

Mouse   150 HARWFPRCQFLLRSKGRDFVERIQTYTPLLGSWDQREEPEDAVSAT-PSAPAHG 202
            |.|..|.|.|:   ||.        ||        :..|.....|| |:.||.|
  Fly   310 HERHSPLCPFV---KGE--------YT--------QNVPLSITYATNPALPAPG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Birc7	NP_001156719.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..47
		BIR	94..161	CDD:237989	26/71 (37%)
		BIR	96..161		26/69 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..225		7/20 (35%)
		zf-C3HC4_3	235..279	CDD:290631
Bruce	NP_001262460.1	BIR	251..321	CDD:279047	26/72 (36%)
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810