DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14220 and suds3

DIOPT Version :9

Sequence 1:	NP_001245759.1	Gene:	CG14220 / 32954	FlyBaseID:	FBgn0031036	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_001003493.1	Gene:	suds3 / 445099	ZFINID:	ZDB-GENE-040801-236	Length:	318	Species:	Danio rerio

Alignment Length:	345	Identity:	135/345 - (39%)
Similarity:	209/345 - (60%)	Gaps:	48/345 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSNYYSLLLQADTYD---DESIGDERSEEDTDDASETEFRSPSRYGAMNGTSNSNNMGTNSELKE 62
            |.:||:...:.|:.|   |.|.....|||||:|||||:..             .::.....|:||
Zfish     1 MVDYYNDEEELDSVDEDEDRSFRGRDSEEDTEDASETDLA-------------KHDEDDYVEIKE 52

  Fly    63 QMYQHKLFNLQKQMEELGQLVHPEYLKRVKKLDSQLKERRRMNEVYKEYMRECVERDYVLEKMAA 127
            ||||.||.:|::|:::|.:....||.||:||||.|.|||.|..:::.:...|.|||:|:.||.||
Zfish    53 QMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERLRNADLFLQLETEQVERNYIKEKKAA 117

  Fly   128 QKEYDEKMMDLKDNLISDFEDRKRQIENERFSIELTNDSMEIKTTITRKLRRRPNEPLPVIEKRR 192
            .||:|:|.::||:|||::.|::|:.:|||:.::|||.||||:|..:|||||||||:|:|:.:|||
Zfish   118 VKEFDDKKVELKENLIAELEEKKKMVENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRR 182

  Fly   193 KPATGQLLVYQLDDKEIESDLKIIQRGRPNPVPQQNGSGSYGSGSQQQQSMHVL---AEPTSNSG 254
            |||..| |.|.|.|::|..||:.:.:.:                |.::|.|.||   |.|:|...
Zfish   183 KPAPAQ-LNYLLSDEQIMEDLRTLNKLK----------------SPKRQGMDVLSFRASPSSPEH 230

  Fly   255 L-----------VETRIEDNKLLYERRWFCRGQQVYVEGKEMSKFAATITAIGNEVVWVKRTNE- 307
            |           .|.|||:.||.|::||:.:.|.:|:|.||.:|.:..|:::|...:||::|::
Zfish   231 LPSTPVDTPSQRYEARIEEGKLYYDKRWYHKSQAIYLESKENTKISCVISSVGTNEIWVRKTSDS 295

  Fly   308 TKVKINMSHLAKGKISIKRR 327
            ||::|.:..|.:|...|:||
Zfish   296 TKMRIYLGQLQRGAFIIRRR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14220	NP_001245759.1	Sds3	58..>171	CDD:285764	55/112 (49%)
suds3	NP_001003493.1	Sds3	44..>160	CDD:285764	55/115 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586482
Domainoid	1	1.000	152	1.000	Domainoid score	I4301
eggNOG	1	0.900	-	-		E1_KOG4466
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15906
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3373
OMA	1	1.010	-	-		QHG50129
OrthoDB	1	1.010	-	-		D1456563at2759
OrthoFinder	1	1.000	-	-		FOG0006361
OrthoInspector	1	1.000	-	-		oto40321
orthoMCL	1	0.900	-	-		OOG6_107707
Panther	1	1.100	-	-	LDO	PTHR21964
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5704
SonicParanoid	1	1.000	-	-		X5317
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800