DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS10b and RPS10-NUDT3

DIOPT Version :9

Sequence 1:	NP_001245758.1	Gene:	RpS10b / 32953	FlyBaseID:	FBgn0285947	Length:	160	Species:	Drosophila melanogaster
Sequence 2:	NP_001189399.1	Gene:	RPS10-NUDT3 / 100529239	HGNCID:	49181	Length:	291	Species:	Homo sapiens

Alignment Length:	154	Identity:	97/154 - (62%)
Similarity:	115/154 - (74%)	Gaps:	6/154 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFMPKAHRVAIYEYLFKEGVIVAKKDFHAQKHPEL--ESIPNLHVIKAMQSLHSRGLVKEQFAWR 63
            |.|||.:|:||||.||||||:|||||.|..|||||  :::|||||:||||||.|||.||||||||
Human     1 MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWR 65

  Fly    64 HYYWYLTNEGIEELRSYLHLPPEIVPSTLKRPARSETVRPRP-AVGGPRGPGDASKTGEDRSAYR 127
            |:|||||||||:.||.||||||||||:||:| :|.||.|||| .:.|.| |...::...||..||
Human    66 HFYWYLTNEGIQYLRDYLHLPPEIVPATLRR-SRPETGRPRPKGLEGER-PARLTRGEADRDTYR 128

  Fly   128 RAPGGSGVDKKGDVGPG-AGEVEF 150
            |:....|.|||.:.|.| |.|.:|
Human   129 RSAVPPGADKKAEAGAGSATEFQF 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS10b	NP_001245758.1	S10_plectin	3..96	CDD:281497	72/94 (77%)
RPS10-NUDT3	NP_001189399.1	S10_plectin	3..97	CDD:308874	72/94 (77%)
RPS10-NUDT3	NP_001189399.1	Nudix_Hydrolase_9	153..250	CDD:240024	97/154 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134225
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101133
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900