DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and CG17707

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_001162627.1	Gene:	CG17707 / 5740408	FlyBaseID:	FBgn0025835	Length:	990	Species:	Drosophila melanogaster

Alignment Length:	767	Identity:	172/767 - (22%)
Similarity:	296/767 - (38%)	Gaps:	199/767 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 FFAQYQNITISDLYRDKEIRLPTTDDLRCLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGN 123
            :|....|:.....::..|||  |.....|..::|.....:.....||.:..||.|.:...:|:||
  Fly   253 YFQLVANLYDHFYWQISEIR--TNVHTGCGLEMQAYLTALHSSYEWAQKAYDSSGRYRGQLLFGN 315

  Fly   124 VIDLGNFDECLGIDHAVTSTHNVQGKYCLSKLQLASSIPTF---LALKTAVCFPASCSADHMDTM 185
            ...||....|..::....:..............:|..:|:.   :.|....|.|.|||    |..
  Fly   316 DKWLGQLSFCYELNRQSLTEERQHFDLQFYVADVALHLPSLNRSMLLSLGECLPKSCS----DID 376

  Fly   186 LRRLLQNLLSIELNPDVPLVSE-GTCKTADREP-------------YD-------------ALTI 223
            ::.:|      .|:|...:::. |...|:.::|             |.             .||:
  Fly   377 VKSIL------SLDPYARMLTVLGAHNTSMQQPPLQILHVRTVPGIYSHWRQLKFQVFISFMLTL 435

  Fly   224 FTIVVLS------------ILCVLMVLATVCDYLVCQDDQPLNKWIKAFSAR------------- 263
            |.:::::            ::..:..::..||....::|....|..:.|..|
  Fly   436 FLVILVASYYQLKIDERRLVVAPIAAISGKCDGTSTKNDVFYGKSFELFQMRPLGCTSSSTDDPE 500

  Fly   264 ----------------------------------------------ANC---------------- 266
                                                          .:|
  Fly   501 VDVNGNRQRCGDSSDMENGVQREFADPNTSTSVGEKSEMGDYQMETGSCAGGTGTYEAKQSVALH 565

  Fly   267 -RILFRLVAPRSNPNVI-----------DCLHGIRVLSFIWVVYGHIYLVSF-FGPNMNLVKLDT 318
             :||. ..|.::|...|           .||||:||.|.:|.:..|.||..| .|.| ...::.|
  Fly   566 QQILL-CFALQTNAKAILNINKTKEIHTACLHGLRVFSVLWTMMVHTYLQMFAIGEN-KFERIIT 628

  Fly   319 WRRSPYSMLVQHAAYSVDTFFFLSGLLMVVIALRAMER--------TKGKLNVSL-MYLHRYLRL 374
             .||.:..::.:|.:|||:|||:||||:.::.|:...:        .|...:.|| |.|:|||||
  Fly   629 -ERSFWYQVIGNATFSVDSFFFISGLLVTMLYLKQNRKYPTETCLFIKSCFSESLMMLLYRYLRL 692

  Fly   375 TPVLALAIIVYMSILPRMG-DGPLYGKVNFDDYSKCKDTWYWTLLYVQNY-ATDEICLGHSWYLA 437
            |||. |.::::.....|.| |..::..... :::.|:..|:..:||:.|| ...|:|:..|||:|
  Fly   693 TPVY-LFVVIFNDFAVRQGLDTSVFQPAKI-EHNTCRMYWWRNILYINNYFPQTEMCMMWSWYMA 755

  Fly   438 VDMQLYIIAPILLICLYKWGKKAAAGILVAMLLLAACLFSIMVIGDVSL-------IAISEGAME 495
            .:||.|::|.:||....|:.|      .||:.|....|.|..:.|.:||       :::...:.:
  Fly   756 NEMQFYVMAALLLALARKYFK------AVAITLFVFLLSSWSISGIISLTYQYTHKVSLPFESFD 814

  Fly   496 KIYFSTHTRASPYLIGILFGYFLH-------VNRGKSFKLSPITVVLGWLTSLALLFSCLFAVY- 552
            .:|.....|...|::|:..||.|:       ::|..:..|        |..||.:|...:|.|:
  Fly   815 FLYDKPWQRVGSYIMGMCTGYVLYKVKTPPLISRRLNLSL--------WACSLFVLLIVVFGVWE 871

  Fly   553 GYAADAEIPPIVEEAFYLTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYI 617
            |:..      ....|||:.....|:..||.|:|.:|..|.....|:.||..:..|||:|:|.||:
  Fly   872 GHLG------TTSSAFYVGVAHTAFGCGLVWIVLSCCWGLVPTVNAILSYRVMWPLSRLTYCAYL 930

  Fly   618 FH---MFMESLNAGITRTNTYFSDYQVMLRFWCDFGFTVLLAFAVYILIEAP 666
            .|   ||:.|.:...|   .:.|:..::..|..:...:...||.:....|||
  Fly   931 IHPIIMFICSSHMSGT---VHLSNPLILTLFLGNAVVSFGCAFVISAFFEAP 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	24/113 (21%)
		OafA	269..667	CDD:224748	126/439 (29%)
		Acyl_transf_3	282..660	CDD:280013	120/418 (29%)
CG17707	NP_001162627.1	NRF	294..399	CDD:214781	24/114 (21%)
		Acyl_transf_3	595..973	CDD:280013	118/404 (29%)
		OafA	597..985	CDD:224748	119/410 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	6	5.920