DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and CG16723

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_651159.3	Gene:	CG16723 / 42781	FlyBaseID:	FBgn0039092	Length:	695	Species:	Drosophila melanogaster

Alignment Length:	708	Identity:	326/708 - (46%)
Similarity:	468/708 - (66%)	Gaps:	47/708 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLVMSLALTSASIRVEHPKNSTLNVGNPEWQSQSYHTISRLRRLAVEFFAQYQNITISDLYRDKE 76
            ||...|..|.|           |.:.:|: .|::|..||:||.|.:||...::|:|:..| ...:
  Fly     8 LLFYGLVATCA-----------LELTDPD-VSKTYEYISQLRPLGLEFAEFFKNVTLESL-GVSD 59

  Fly    77 IRLPTTDDLRCLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGNVIDLGNFDECLGIDHAVT 141
            .:|.:.:|..|..:|..:...:|.|:.|||:|||:||:.|:|:|.||:.|||||||||.|: .|.
  Fly    60 SKLASAEDELCSVELAAVMNGISLRETWALKMIDAWGSIPNGLLTGNLFDLGNFDECLSIE-KVV 123

  Fly   142 STHNVQGKYCLSKLQLASSIPTFLALKTAVCFPASCSADHMDTMLRRL--LQNLLSIELNPDVPL 204
            ....::||:|   ..||:|      .:.|.|||||||:..|:|.:.:|  |.||.|..|.   ..
  Fly   124 GGKRIRGKFC---FLLANS------ARIATCFPASCSSTQMETFVEQLMALINLNSSSLK---MR 176

  Fly   205 VSEGTCKTADREPYDALTIFTIVVLSILCVLMVLATVCDYLVCQDDQPLNKWIKAFSARANCRIL 269
            :|..:|:|::.||::.|||||||:||::||:::..|:.||.:|.|.:.:...:|.||||||.|.|
  Fly   177 ISGASCQTSEIEPWNGLTIFTIVILSLMCVIVISVTIFDYFLCDDPRSIPAVVKTFSARANSRAL 241

  Fly   270 FRLVAPRSNPNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPNMNLVKLDTWRRSPYSMLVQHAAYS 334
            ||:|..:||||||:|.||||.::..||:|.|.::.....||:|.:.|.||...|:|..|.|..::
  Fly   242 FRIVPNKSNPNVIECFHGIRCMTLFWVIYCHEFIFFLTSPNLNRLDLYTWTVKPFSSFVLHGYFA 306

  Fly   335 VDTFFFLSGLLMVVIALRAMERTKGKLNVSLMYLHRYLRLTPVLALAIIVYMSILPRMGDGPLYG 399
            ||:||.|.|||:.:|:||:||::.|:||..||||||.||:.||:|:||::||:::..:..||:.
  Fly   307 VDSFFVLGGLLVSMISLRSMEKSGGRLNPVLMYLHRILRILPVVAIAILIYMTMMTVVSGGPML- 370

  Fly   400 KVNFDDYSKCKDTWYWTLLYVQNYATDEICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGI 464
            |..:.....|.:.|:||||::||||...|||.|:|||||||||:||:||||:.||.||||||:||
  Fly   371 KNGYHGMEYCLNGWFWTLLFIQNYAVQNICLDHTWYLAVDMQLFIISPILLMALYNWGKKAASGI 435

  Fly   465 LVAMLLLAACLFSIMVIGDVS-LIAISEG----AMEKIYFSTHTRASPYLIGILFGYFLHVNRGK 524
            .|.::||:.|||:..::...: ||.|::|    ..:|:|.:|||.|:|:|||.|||||||:||||
  Fly   436 AVLVVLLSGCLFATQMVNHYTLLIKINDGDDGVPNKKLYLATHTHAAPWLIGFLFGYFLHINRGK 500

  Fly   525 SFKLSPITVVLGWLTSLALLFSCLFAVYGYAADAEIPPI--VEEAFYLTFTRIAWPLGLCWVVFA 587
            .|:||...|.|||:.|||:||:.:||:|. |:....||:  :||:.|.|.||:||||.:||::||
  Fly   501 KFQLSRPIVWLGWILSLAMLFTSIFALYP-ASQLTAPPLSTLEESLYYTLTRLAWPLAICWIIFA 564

  Fly   588 CMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRFWCDFGFT 652
            ||.|||||||||||:|||||||:||||.||:|||::.:|:...||||||::|..|.||..|.|||
  Fly   565 CMQGYGGLANSFLSTPLWQPLSRLSYSMYIWHMFVQEVNSRNVRTNTYFTNYIAMERFCYDLGFT 629

  Fly   653 VLLAFAVYILIEAPFGNLEGLLLPDKRPCPPRPAVEESKEAPVGGCSASAPTLENKTP 710
            ||:::.:|::||||....:.:|...|.|..|..|...|.|.          .:||:.|
  Fly   630 VLMSYILYLIIEAPLCGFDSILRGRKDPPAPNKANIISNER----------GMENRDP 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	48/111 (43%)
		OafA	269..667	CDD:224748	215/404 (53%)
		Acyl_transf_3	282..660	CDD:280013	202/384 (53%)
CG16723	NP_651159.3	NRF	87..184	CDD:214781	48/109 (44%)
		Acyl_transf_3	254..599	CDD:280013	184/346 (53%)
		OafA	291..644	CDD:224748	191/354 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458059
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	13	12.750