DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and CG11353

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_647915.1	Gene:	CG11353 / 38560	FlyBaseID:	FBgn0035557	Length:	754	Species:	Drosophila melanogaster

Alignment Length:	779	Identity:	176/779 - (22%)
Similarity:	318/779 - (40%)	Gaps:	149/779 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LVMSLALTSASIRVEHPKNSTLNVGNPEWQSQSYHTISRLRRLAVEFFAQYQNITISDLYRDKEI 77
            ::|.|.|...|:..:...|.:....:..||......::....|..|........|| :::...|.
  Fly    16 VLMLLGLWLGSVLAKGASNQSATTNSHAWQRYHSQALNASPALPDELEILDAPSTI-EIHSPHET 79

  Fly    78 RLPTTDDL--------------RCLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGNVIDLG 128
            .|..|..:              :|.|.|:.:.:.:..::.||::::|:.||.|||.:||....||
  Fly    80 HLTRTSVIFGLTKVANESSVSQKCHAQLRQMQRGILGKQPWAMKVLDASGTKPSGFVYGQNYWLG 144

  Fly   129 NFDECLGIDHAVTSTHNVQGKYCLSK-----------------------LQLASSIPTFLALK-- 168
            :.:.|.|:...|..|        |||                       |.|..:.|..:.:|
  Fly   145 SREACRGVQRPVGIT--------LSKNFDRVMHYGIITQQAPFDMDYRVLYLRHNSPWQVEIKLM 201

  Fly   169 ------TAVCFPASCSADHMDTMLRRLLQNLLSIE-----LNPDVPLVSEGTCKTA--DREPYDA 220
                  ..:|.|::||:..:.::.:..:...:..|     :.|:|..:.:...|..  :|..:..
  Fly   202 SEQIIHIGLCLPSACSSVEVQSLAQDYVAGGMFTENEIFDIKPEVVYMKDLQLKDEFFERASFRL 266

  Fly   221 LTIFTIVVLSIL-CVLMVLAT----------------------------------VCDYLVCQDD 250
            |....::.:::: |...:.||                                  :..|:.|. |
  Fly   267 LVACVLLTVTLMFCAQQLHATSKMPSISVDPLDRDLAPAESEIWRGLNSLLQIERLQRYVTCW-D 330

  Fly   251 QPLNKWIKAFSARANCRILFRLVAPRSNPNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPNMNLVK 315
            .|.| |.|.|:.|.|            ..|.|..::|:|.:..||::..|:....:|..: |...
  Fly   331 VPGN-WAKIFAIREN------------TANEIPLMNGLRSVCAIWIMVFHVVWFMYFTVH-NKTV 381

  Fly   316 LDTWRRSPYSMLVQHAAYSVDTFFFLSGLLMVVIALR------AMERTKGKLNVSL---MYLHRY 371
            |.::....:...|..|...||.||.:||.|.....||      |:.:.....|:.|   :..|||
  Fly   382 LISYAEQAFFQYVSSAPLLVDVFFTISGFLQTFNFLRNSRQLEAVRQNSFSENLKLFGKLLFHRY 446

  Fly   372 LRLTP----VLALAIIVYMSILPRMGDGPLYGKVN--FDDYSKCKDTWYWTLLYVQN-YATDEIC 429
            |||.|    |:|...:||..|    ||..:| .:|  ||:  .|...|:..||::|| :...::|
  Fly   447 LRLGPLYLVVMATVDLVYAYI----GDVSVY-HINERFDE--MCTRHWWRNLLFIQNLFDHRDMC 504

  Fly   430 LGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGILVAMLLLAACLFSIMVIGDVSL---IAISE 491
            ...||.||.:||.:|:|..||....|:.|...:.::.:.:...|..:.|.:.....|   .|.:.
  Fly   505 ANWSWSLACEMQFFILANALLFLYVKYPKVVKSLVVSSFVATIAWSYGIGLSIKFQLSFDAAFAT 569

  Fly   492 GAMEKIYFSTHTRASPYLIGILFGYFLHVNRGKSFKLSPITVVLGWLTSLALLFSCLFAVYGYAA 556
            |.  :||.|...|..||::|.:..:.|..|| ...::|.......|..:|.:.|:|:::    ..
  Fly   570 GT--EIYTSPFVRVLPYILGAVTAWLLQENR-VQLEISEQKERACWHFALFVFFACIYS----TV 627

  Fly   557 DAEIPPIVEEAFYLTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMF 621
            ..::.|::....:: ..|:.:.|.:||::.....|.|...:..|.:..:|.:|:|||:.|:.:..
  Fly   628 KRDLGPLMAITLFV-MGRLFFSLSVCWMIARSCDGRGVWWSRLLEAKGFQHVSRLSYAIYLLNPL 691

  Fly   622 MESLNAGITRTNTYFSDYQVMLRFWCDFGFTVLLAFAVYIL-IEAPFGNLEGLLLPDKRPCPPR 684
            :.:|...:|..:|:...:.:.: ..|.|...|.||..::.| .|.||.||..||  ::|...|:
  Fly   692 VIALFYSLTNASTHADPFMLCV-VTCGFAVIVYLASILFSLAFELPFSNLSSLL--NRRQSKPK 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	30/145 (21%)
		OafA	269..667	CDD:224748	105/417 (25%)
		Acyl_transf_3	282..660	CDD:280013	102/396 (26%)
CG11353	NP_647915.1	NRF	118..243	CDD:214781	28/132 (21%)
		OafA	349..752	CDD:224748	111/421 (26%)
		Acyl_transf_3	352..729	CDD:280013	101/393 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850