DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and CG42329

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster

Alignment Length:	630	Identity:	270/630 - (42%)
Similarity:	394/630 - (62%)	Gaps:	36/630 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 CLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGNVIDLGNFDECLGIDHAVT----STHNVQ 147
            |||:::.|......:.|.|||:.|:||.||.|:|||:.:|:||::.||.:|.:.:    .|.|..
  Fly    56 CLAEVRLLLTGAEAKSLPALRVFDAWGKFPQGLLYGHFMDMGNYESCLSLDLSKSLGNVMTINAG 120

  Fly   148 GKYCLSKLQLASSI-----PTFLALKTAVCFPASCSADHMDTMLRRLLQNLLSIELNPDVPLVSE 207
            .|||||::|..|.:     ...|.|....|.|:||||..:...:...|:::.. :.:.:..||.|
  Fly   121 AKYCLSRMQFESLLMEAAGADALTLSIGTCIPSSCSAAQLSRWMSGHLKDMFG-QNSTEATLVQE 184

  Fly   208 GTCKTADREPYDALTIFTIVVLSILCVLMVLATVCDYLVCQDDQPLNKWIKAFSARANCRILFRL 272
            ..|..|.|:|.:.|....:.:|.:||::::|||:.||....     ||.:.:||.|.|...|.:
  Fly   185 KDCSLAHRDPMNGLDWLAVSILILLCIVVLLATILDYSCVS-----NKLLSSFSLRKNVPQLLK- 243

  Fly   273 VAPRSNPNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPNMNLVKLDTWRRSPYSMLVQHAAYSVDT 337
            .:...:|.||.||:|||.|:.||::.||.|:.....|.:|...:..|.:.|:||::|....||||
  Fly   244 TSNTPSPRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVAWAQMPFSMILQSGTTSVDT 308

  Fly   338 FFFLSGLLMVVIALRAMERTKGKLNVSLMYLHRYLRLTPVLALAIIVYMSILPRMGDGPLYGKVN 402
            ||.|||||:|:.|||.|:|:||:|:|.||||||.:|||||||||::::|::.||:..|||:.:
  Fly   309 FFLLSGLLLVLSALREMDRSKGRLHVPLMYLHRLVRLTPVLALAVLIFMTLFPRLDSGPLWNQ-- 371

  Fly   403 FDDYSK-CKDTWYWTLLYVQNYAT-DEICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGIL 465
            |...|: |.|||:.|||||||||. ..:|||||||||||||||||:|:|||.||||||||.|||:
  Fly   372 FTSSSELCSDTWWATLLYVQNYAAPGRMCLGHSWYLAVDMQLYIISPLLLIALYKWGKKAIAGIV 436

  Fly   466 VAMLLLAACLFSIMVIGDVSL------IAISEGAMEKIYFSTHTRASPYLIGILFGYFLHVNRGK 524
            :.:|||:.|:|.|:::.|:.:      :......|..||::||.||:|:|||:|||||||....:
  Fly   437 LLILLLSGCVFGIVMLRDLKVFDRYGNLGGDSTEMRLIYYTTHARATPWLIGLLFGYFLHHQNVR 501

  Fly   525 SFKLSPITVVLGWLTSLALLFSCLFAVYGY----AADAEIPPIVEEAFYLTFTRIAWPLGLCWVV 585
            ..:|.....::.|:.||::|.:.:||||.|    |.|..   .:..||||..:||||||.|||::
  Fly   502 KTRLPKWLALVLWILSLSMLATVIFAVYPYTQSGAGDIS---AMAGAFYLCCSRIAWPLALCWII 563

  Fly   586 FACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRFWCDFG 650
            :||.:|...:.|.|||...|||||||||..||:|:.:|:::....:|:.:||||..:||||.|||
  Fly   564 WACQNGLAPIVNEFLSWSFWQPLSKLSYCLYIWHLLVETVHIARIKTSLHFSDYDAILRFWSDFG 628

  Fly   651 FTVLLAFAVYILIEAPFGNLEGLLL---PDKRPCPPRPAVEESKE 692
            .|:.::..:::.:|.|.|.||..||   ..|...|..|.|:.|.|
  Fly   629 ITLFVSMFMHLCVEVPLGRLEMELLKRCQKKEDSPESPRVDPSTE 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	41/118 (35%)
		OafA	269..667	CDD:224748	195/409 (48%)
		Acyl_transf_3	282..660	CDD:280013	191/389 (49%)
CG42329	NP_608590.2	NRF	71..179	CDD:214781	37/108 (34%)
		OafA	253..648	CDD:224748	194/399 (49%)
		Acyl_transf_3	253..639	CDD:280013	191/390 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458084
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	12	11.800