DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and Oacyl

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	XP_036017063.1	Gene:	Oacyl / 319888	MGIID:	2442915	Length:	717	Species:	Mus musculus

Alignment Length:	727	Identity:	183/727 - (25%)
Similarity:	303/727 - (41%)	Gaps:	160/727 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 LRCLADLQTLAKDVSD--RKLWALRMIDSWGTFPSGILYGNVIDLGNFDECLGIDHAVTSTH--- 144
            |:|:.|......|::.  .|.:||||.||.|...|.:|.|||..||::.|||       ||.
Mouse    25 LKCMQDTDEFLSDLNSLKPKEYALRMYDSVGKLGSNVLTGNVDRLGSYSECL-------STRSPK 82

  Fly   145 -NVQGKYCLSKLQLASSIPTFLALKTAVCFPASCSADHMDTMLRR--------LLQNLLSIE--- 197
             :.:|:||  ||.:......:   ...||.|.||:.:.: ||:.:        |..:..|::
Mouse    83 GSFRGQYC--KLHILQDGTDY---SVGVCVPDSCAEEDV-TMMSQLDKPSFFDLYTHHASLDCRH 141

  Fly   198 -----------------------LNPDVPLV---SEGTCKTADREPYDALT--IFTIVVLSIL-- 232
                                   |.|.:.|.   |..:|:...|....|::  :|..|.|.|.
Mouse   142 TMSPCPTKISLFLGTLKFRNTSFLEPSLSLFTKDSSSSCEVVARCAAGAMSPDMFASVCLFITLL 206

  Fly   233 -CVLMVLATVCDYLVCQD-------------------DQPL-NKWIKAFSARANCRILFRLVAPR 276
             .||.|..||  |:|.:|                   ..|| |.......:||:|::   .:.|.
Mouse   207 GLVLPVAGTV--YMVARDWGLDLRTSSVHGTPPTSCESLPLRNMESNRQRSRASCQV---QLPPP 266

  Fly   277 SNPN-----------VIDC----------------------LHGIRVLSFIWVVYGHIYLVSFFG 308
            ..|:           |:.|                      |:||||||.:||:.||...::.:
Mouse   267 GAPSRGRRFLGAVDEVLQCFSWQKNMPAICSPELPGGTCRTLNGIRVLSLLWVISGHTSQMTAW- 330

  Fly   309 PNMNLVKLDTWR-RSPYSMLVQHAA-----YSVDTFFFLSGLLMVVIALRAMERTKGKLNVSLM- 366
              ::|..:..|: |.|.:.|..::.     ..|||||.:||.|.....|:..:.|...:...::
Mouse   331 --LSLDNVLEWKSRVPENPLYLYSRSGPFYLGVDTFFLISGWLSARSFLKMHQNTSTGITPKVIL 393

  Fly   367 --YLHRY--LRLTPVLALAIIV-YMSILPRMGDGPLYGKVNFDDYSKCKDTWYWTLLYVQNY-AT 425
              :|.|:  |:|..:.::.::| :.|.:|.   ||::....| .:..|::.|:..||.:.|: :.
Mouse   394 RYFLKRFTRLQLLHMYSVCLLVGFFSFVPW---GPVWEVAQF-HWDNCREVWWTNLLLLNNFLSV 454

  Fly   426 DEICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGILV-AMLLLAACLFSIMVIGDVSLIAI 489
            ...|.|.:||||.|.|.::..|::   .:..||.....:|: .:|.||:...:.::.....|...
Mouse   455 QNACNGWTWYLASDFQFHLTTPLI---FFVHGKSKRVFVLLGGLLFLASSTATTLLTLAYKLPVA 516

  Fly   490 SEGAMEK----IYFS-----THTRASPYLIGILFGYFLHVNRGKSFKLSPITVVLGWLTSLALLF 545
            |..|..:    :|||     .:.|..|:|:|:....|:|.:.......:.:..:|||..||..||
Mouse   517 SPAAASEHGTVLYFSEYYTKPYCRCGPFLVGLFLSMFMHSDHPTDILKTTVQAMLGWTWSLLTLF 581

  Fly   546 SCLFAVYGYAADAEIP-PIVEEAFYLTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLS 609
            :.:  ...|..|...| ..|..|.|....|..|...:.||:|||..||||.....||..:|...:
Mouse   582 AVV--ALAYVLDDTSPTSSVAAAIYQALHRTLWAAAVGWVIFACQEGYGGPVKRMLSWGIWSLPA 644

  Fly   610 KLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRFWCDFGFTVLLAFAVYILIEAPFGNLE-GL 673
            .:||:.|:.|..:..|..|:..|..:::|..::..|:.....|.|....:.:.||.|:..|: ||
Mouse   645 SISYACYLVHPIVIILYNGLQETLIHYTDTNMLYLFFGHCVLTFLGGLVLTLFIERPWQELKWGL 709

  Fly   674 LLPDKRPCPPRP 685
            ..|:    |.||
Mouse   710 WGPE----PARP 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	39/150 (26%)
		OafA	269..667	CDD:224748	112/454 (25%)
		Acyl_transf_3	282..660	CDD:280013	107/423 (25%)
Oacyl	XP_036017063.1	NRF	44..122	CDD:214781	32/90 (36%)
Oacyl	XP_036017063.1	OafA	308..710	CDD:224748	111/413 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843232
Domainoid	1	1.000	52	1.000	Domainoid score	I11359
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	192	1.000	Inparanoid score	I3845
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm42659
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4398
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.630