DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and drd

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	699	Identity:	183/699 - (26%)
Similarity:	310/699 - (44%)	Gaps:	100/699 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 RLPTTDDLRCLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGNVIDLGNFDECLGIDHAVTS 142
            |.|....| |...:......:.:..||||:|.||.|...||||.||:...|:||:||||...:..
  Fly   146 RNPDASTL-CRRQMHQFLNALDNFDLWALKMHDSSGKLNSGILNGNINQPGDFDQCLGIQQRMNQ 209

  Fly   143 THN----------VQGKYCLSKLQ---------------LASS--------------IPTFLALK 168
            ..:          ::|:|||:..|               |..|              :|.:..:.
  Fly   210 DQDAGQDQDGDSIIRGQYCLAYAQPVLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSLIN 274

  Fly   169 TAVCFPASCSADHMDTMLRRLLQN-------LLSIELNPDVPLVSEGTCKTADREPYDALTIFTI 226
            ..:|.|:.|||..::..:...|.|       ..::.:.|.:       |:..|:.|:|..|.:.:
  Fly   275 WGLCVPSGCSARDVEYSVAEYLGNQTASTGITFNVRVEPQM-------CQVRDQRPWDRNTTWAV 332

  Fly   227 VVLSILCVLMVLATVCDYLVCQDDQP-LNKWIKAFSARANCRILFRLVAPRSNPNVIDCLHGIRV 290
            ....::..:.||:|:.|.  ....|| .|.|..|||...|.|.||   :..|.|..|:.:||||.
  Fly   333 RFFLLVLSVAVLSTIYDR--STKSQPKQNPWFTAFSLDKNLRWLF---STSSAPGDIEAVHGIRF 392

  Fly   291 LSFIWVVYGHIYLVSFFGPNMNLVKLDTWRRSPYSMLVQHAAYSVDTFFFLSGLLMVVIAL-RAM 354
            |:.|.:::.|..:..||.|..|...:......|::::.:.|:...|.|...||:|...... |.|
  Fly   393 LNAIMLIFSHKSMAMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGRLM 457

  Fly   355 ERTKGKLNVSLMYLHRYLRLTPVLALAIIVYMSILPRMGDGPLYGKVNFDDYSKCKDTWYWTLLY 419
            ::...:|...  |:.|.:|:.|.||..|:....:||..|.||.:..|.......||..|:..||:
  Fly   458 KQQPIRLKNE--YISRLMRIVPPLAALILFCTYVLPLWGSGPQWNLVVGHHADICKKNWWRNLLF 520

  Fly   420 VQNY-ATDEICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGILVAMLLLAACLFSIMVIGD 483
            :.|| ...|:||.|:.:|.:|.:|:.:||:|::.|::|.::....:|:...:..|..:...::..
  Fly   521 IHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLFALLLLCTVGTAARYYTTIVNQ 585

  Fly   484 VSLIAISEGAMEKIYFSTHT----------------RASPYLIGILFGYFLHVNRGKSFKLSPIT 532
            :|         ..|||.|:.                |::.|::|||.||.|  .:.::.:||.:.
  Fly   586 LS---------NYIYFGTNIQRLFRTADYMYSFPPHRSTVYIMGILLGYVL--RKYQNARLSSLQ 639

  Fly   533 VVLGWLTSLALLFSCLFAVYGYAADAEIPPI---VEEAFYLTFTRIAWPLGLCWVVFACMHGYGG 594
            :.||||.:...:.:.|.   |.|...:|..:   ...|.|..|..|||.|...|:||...:||..
  Fly   640 LRLGWLVATVCVLASLL---GPAPMGDINYVYNSTHAAIYAAFAPIAWCLFFSWIVFVSHNGYTN 701

  Fly   595 LANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRFWCDFGFTVLLAFAV 659
            ......:...:|..:||||:.|:....:...|.|..|...::.::..::....:|....|.:.|:
  Fly   702 KLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNVGRRRHIHHYYNFVSIILDTNEFISIFLASVAL 766

  Fly   660 YILIEAPFGNLEGLLLPDKRPCPPRPAVEESKEAPVGGCSASAPTLENK 708
            .:|.:|||.||:.||:  |||...: .|::||........|:..||.::
  Fly   767 TVLFDAPFQNLKKLLI--KRPTAAK-VVKDSKAKAAESQDATTTTLASQ 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	38/155 (25%)
		OafA	269..667	CDD:224748	109/418 (26%)
		Acyl_transf_3	282..660	CDD:280013	103/398 (26%)
drd	NP_001033845.1	NRF	169..>289	CDD:214781	34/119 (29%)
		OafA	371..791	CDD:224748	119/441 (27%)
		Acyl_transf_3	384..770	CDD:280013	103/401 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920