DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and oac-32

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	698	Identity:	201/698 - (28%)
Similarity:	303/698 - (43%)	Gaps:	140/698 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 TISDLYRDKEIRLPTTDDL--RCLADLQTL---------------------AKD--VSDRKLWAL 106
            |.|..::| .|:....|:|  :||.|..|.                     ||:  |....|:|:
Worm    18 TTSATWKD-VIKPKPLDNLSAQCLNDTNTWINSLEIFGTLYAECIIMKKCNAKELKVLRDNLYAV 81

  Fly   107 RMIDSWGTFP-SGILYGNVIDLGNFDECLGIDHAVTSTHNVQGK-----YCLSKL----QLASSI 161
            :.:|::|.|| :|:|....:..|::.||          ..|.||     ||...|    .::|..
Worm    82 QQLDAFGQFPGAGLLELKTLYDGSYQEC----------QRVSGKKYDVNYCYLLLTPGKNVSSCA 136

  Fly   162 P-------TFLALKTAVCFPASCSADHMDTMLRRLLQNLLSI--ELNPDVPLVSEGTC---KTAD 214
            |       :.|.|:.|||.|.||  :|         |:::.|  ||:|.........|   :...
Worm   137 PSNSKSLYSQLPLRIAVCLPDSC--NH---------QDMIDIFNELSPYPFTACSAYCTKNEVKK 190

  Fly   215 REPYDALTIFTIVVLSILCVLMVLATVCDYL--------VCQDDQPLNKWIKAFSARANCRILFR 271
            ..|:...:||.||::    |:..:|::.||:        ..:::....|.:..||...|..:|..
Worm   191 DTPFWGFSIFLIVMV----VIAAIASIVDYVRETVYGLSSQKENNTFFKILLTFSLWTNAELLLS 251

  Fly   272 LVAPRSN-PNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPNMNLVKLD----TWRRSPYSMLVQHA 331
            :...:|. ...:||   ||:||..|||.||.:|.......:..| ||    .|..     |:.:|
Worm   252 VKEQKSGFIKSLDC---IRLLSMCWVVTGHSFLYLILADTLEPV-LDFPTYFWNH-----LLLNA 307

  Fly   332 AYSVDTFFFLSGLLMVVIALRAMERTK---GKLNVSLMYLHRYLRLTPVLALAIIVYMSILPRMG 393
            ..||||||.|||:::..:..:.....|   ..:...|.|:||||||||.:.|.|..:....|.:.
Worm   308 FVSVDTFFVLSGIVVAYLFFKTKLTKKTITSPMTWILFYVHRYLRLTPPVMLFIGFFTVYTPYIQ 372

  Fly   394 DGPLYGKVN--FDDYSKCKDTWYWTLLYVQNY----ATDEICLGHSWYLAVDMQLYIIAPILLIC 452
            ......::|  ....:.||..|:..|||:.|:    :.:..|.|.:||||||.|||::|||:|:.
Worm   373 GAFSASELNQMAPQAAACKTLWWQNLLYINNFDDGNSQNSTCYGITWYLAVDTQLYLVAPIVLVA 437

  Fly   453 LYKWGKKAAAGILVAMLLLAACLFSIMV------IGDVSLIAISEGAMEKI----YFSTHTRASP 507
            ||   ...|||   ..:::|.|:.||:.      :.:|....|..|...|.    |.....|..|
Worm   438 LY---FSFAAG---TAIIVAGCVGSIITTYILFGVYNVPADIIGNGDQTKFFNIAYSKPWIRCPP 496

  Fly   508 YLIGILFGYFLHVNRGKSFKLSPITVVLGWLTSLALLFSCLFAVYGYAADAEIPPIVEEAFYLTF 572
            ||:|:|.||.|.....:..:|:....:.||:|:..:...||||.|.|...|.........|| .|
Worm   497 YLVGLLTGYLLATYGSRKIRLNWALAIAGWITAFVIAGFCLFATYDYDKGAHWSTFTRATFY-NF 560

  Fly   573 TRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNTYFS 637
            .|:.|.:.:||||.|...|:||..:.|:|.|:|||..:|||.|||.|..:......:.....|.|
Worm   561 HRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVLYYYLNVGGVLHYSS 625

  Fly   638 DYQVMLRFWCDFGFTVL----------LAFAVYILIEAPFGNLEGLLL 675
            .:||         ||.:          |||....|.|.|...||.:|:
Worm   626 AWQV---------FTYIAIPATLLSYVLAFFWSCLFEVPILKLEKMLI 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	34/131 (26%)
		OafA	269..667	CDD:224748	137/431 (32%)
		Acyl_transf_3	282..660	CDD:280013	133/410 (32%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	34/128 (27%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	137/429 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.680