DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and oac-50

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_001309487.1	Gene:	oac-50 / 179284	WormBaseID:	WBGene00020864	Length:	731	Species:	Caenorhabditis elegans

Alignment Length:	708	Identity:	163/708 - (23%)
Similarity:	292/708 - (41%)	Gaps:	151/708 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SRLRRLAVEFFAQYQNITISDL-YRDK-EIRL--PTTDDL------RCLADLQTLAKDV---SDR 101
            ||::.|.:.     .:.:|..| ||:| |||.  ..|.||      |...:|.:|....   ||.
Worm    26 SRIQALLLN-----SSFSIEQLDYRNKNEIRSGEVATPDLCKTLMKRWFQNLNSLKNGTCKNSDD 85

  Fly   102 KLWALRMIDSWGTFPSGILYG--NVIDLGNFDECLGIDHAVTSTHNVQG----KYCL-----SKL 155
            .|.||..:|::..:|:.   |  |:.| |:|.:|..:        |.:|    |||.     .|:
Worm    86 CLDALDQLDAFARYPAP---GSPNIYD-GSFRKCNDL--------NEKGGHRRKYCYLIQADEKM 138

  Fly   156 QLASSIPT--FLALKTA--VCFPASCSADHMDTMLRRLLQNLLSIELNPDVPLVSEGTCKTAD-- 214
            .......:  |...:||  .|.|..|......:|...:.:....:...|    |....|...|
Worm   139 NCREEYHSILFKPNRTAFGFCGPEICHGKDYASMFGSMEKTFHFLMDRP----VCAAFCTVRDIP 199

  Fly   215 -REPYDALTIFTIVVLSILCVLMVLATVCD--YLVCQDDQPL--NKWIKAFSARANCRILFRLVA 274
             :..:...|.|.|::.|::....:...|.|  |.:..:.:.:  .:.|.:||..:|...:|:
Worm   200 KKLQFYFFTAFLIMLGSVVFFSSLYDYVRDTRYRLSSESEKVFGQRIILSFSLWSNIEFIFQ--- 261

  Fly   275 PRSNPNVIDCLHGIRVLSFIWV----VYGHIYLVSFFGPNMNLVKLDTWRRSPYSMLVQHAAYS- 334
             ...|:.|..|..||.::|.||    |.||:   .|:.        |..|..|..:.:..:|.|
Worm   262 -DKRPDYIRSLDCIRAITFTWVVGQNVVGHL---GFYD--------DKIRVDPSKISLASSAMSS 314

  Fly   335 ---VDTFFFLSGLLMVVIALRAMERTKGKLNVSLM---------YLHRYLRLTPVLALAIIVYMS 387
               :.|:.|:|||.:....|      |||.::.::         :.||::|||.    |::|::.
Worm   315 LLPIYTYLFMSGLTVSYTFL------KGKPSLDVLKQPFTWLIFFFHRWIRLTS----ALMVFIG 369

  Fly   388 ILPRMG---DGPL-----YGKVNFDDYSKCKDTWYWTLLYVQNY-ATDEICLGHSWYLAVDMQLY 443
            .....|   .||.     |..|...|.  |  |::..::::.|: |.||:|...:|:||||.|..
Worm   370 FFDAYGKYIQGPYDALTGYSMVTQTDL--C--TYWMDIIHISNFVAVDEMCYLPAWHLAVDFQFT 430

  Fly   444 IIAPILLICLYKWGKKAAAGILVAML--LLAACLFSIMVIGDVSLIAISEG-------AMEKIYF 499
            |.||..|:..:   .....|.::|::  |:.:.|.....:.:..|.:...|       .:|.|..
Worm   431 IFAPFFLLAFH---YSTVLGTILAIIASLIGSGLTVFFFLQNTILNSAFTGDHVHDDKLVEIILS 492

  Fly   500 STHTRASPYLIGILFGYFLHVNRGKSFKLSPITVVLGWLTSLAL-LFSCLFAVYGYAADAEIPPI 563
            ....:.:||::|::.|..|..:.|....:.|:...:.|:....| |.:.:|..:|.:.
Worm   493 KPWNQMAPYMMGMIAGCILGKHSGSKRIIHPVASSIIWIIITVLGLVALIFGHFGTSQ------- 550

  Fly   564 VEEAFYLTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFH----MFMES 624
            :|:|.....||..|.:.|.|::.:......|....:|..|.|:|..|||:.|:|.|    .|:.:
Worm   551 LEKALTNVSTRAVWSICLMWIIISTELKSAGPIGHYLEHPFWRPFGKLSFCAFIVHHMLLYFLFN 615

  Fly   625 LNAGITRTNTYFSDYQVMLRFWCDFGFTV-------LLAFAVYILIEAPFGNLEGLLL 675
            :.....:..:::.:|         |.:|:       .|||.:.:::|.|...::.|::
Worm   616 IQEEAPKYTSFWHEY---------FHYTIPIVIYSYFLAFFLSVVVEIPILRIDRLII 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	27/124 (22%)
		OafA	269..667	CDD:224748	103/444 (23%)
		Acyl_transf_3	282..660	CDD:280013	100/424 (24%)
oac-50	NP_001309487.1	NRF	86..195	CDD:214781	27/124 (22%)
oac-50	NP_001309487.1	Acyl_transf_3	268..646	CDD:376607	98/421 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730