DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and oac-31

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_503441.2	Gene:	oac-31 / 178643	WormBaseID:	WBGene00018707	Length:	705	Species:	Caenorhabditis elegans

Alignment Length:	748	Identity:	205/748 - (27%)
Similarity:	330/748 - (44%)	Gaps:	131/748 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LVMSLALTSASIRVEHPKNSTLNVGNPEWQS----QSYHTISRLRRLAVEFFAQYQNITISDLYR 73
            ||:||.|         |.:..::..|..|:.    :..|.:|.            :.:..:|.:.
Worm     7 LVLSLFL---------PFSHCISTMNSNWKDIFDPKPLHDLSE------------KCLNDTDTWL 50

  Fly    74 DKEIRLPTTDDLRCLA--DLQTLAKDVSDRKLWALRMIDSWGTFPS-GILYGNVIDLGNFDECLG 135
             |.:.:.:|..:.||.  :..|....:.|..|:|::.:|::|.||: |:|....:..|::.||..
Worm    51 -KSLEIFSTVSVECLTLNNCTTQESKILDENLYAVKQLDAFGEFPTPGLLELRTLYDGSYQECDR 114

  Fly   136 IDHAVTSTHNVQGKYCLSKLQL-------ASSIPTFLALKTAVCFPASCSADHMDTMLRRLLQNL 193
            ||.....|:     ||...|..       |.|:.:.:.|:.|||.|.|||  |.|.:      |:
Worm   115 IDGERYKTN-----YCYLILNFGKNISCSAPSVYSNVTLRMAVCLPDSCS--HQDMI------NI 166

  Fly   194 LSIELNPDVPLVSEGTC--KTADRE-PYDALTIFTIVVLSILCVLMVLATVCDYLVCQDD----- 250
            .: :|:|......:..|  .|.::: |:...|:|..:|:::    .:.||:.||:  ||.
Worm   167 FN-QLSPYPFTACDAYCVKNTVEKDVPFWGFTVFLTIVIAV----AIFATLLDYV--QDAVLGLS 224

  Fly   251 --QPLNKWIK---AFSARANCRILFRLVAPRSNPNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPN 310
              :..|.:||   .||...|..::  |......|..|..|..||.||..||:.||.::.
Worm   225 NLKEKNIFIKIILTFSLWTNAELI--LSVKEHKPGFIKSLDCIRGLSIFWVITGHSFIY------ 281

  Fly   311 MNLVKLDT------WRRSPYSMLVQHAAYSVDTFFFLSGLLMVVIALRAMERTK---GKLNVSLM 366
              :.:.||      ::...::.|:.:|..|||:||.|||:::..:..:.....|   ..:...|.
Worm   282 --MTQADTMKPVMEFQNQFWNHLIINAPVSVDSFFALSGIVVAYLFFKMKPNIKMAASPVTWILF 344

  Fly   367 YLHRYLRLTPVLALAIIVYMSILPRMGDGPL---YGKVNFDDYSKCKDTWYWTLLYVQNYATDE- 427
            |:||||||||.:.:.|..:....|.: .||.   :..|.|.....|||.|:..|||:.|:...:
Worm   345 YVHRYLRLTPTVMIFIGFFTVYFPYV-QGPFAASFSNVQFPQVEACKDYWWHNLLYINNFDNSQH 408

  Fly   428 ----ICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGILVAMLLLAACLFSIMV------IG 482
                .|...:||||||.||||:|||:||.|:   ...|.|   ..:::|.|:.||:.      :.
Worm   409 RERNTCYAITWYLAVDTQLYILAPIVLIALF---FSFAVG---TAIIVAGCVGSIIATYILFDLY 467

  Fly   483 DVSLIAISEGAMEKIYF------STHTRASPYLIGILFGYFLHVNRGKSFKLSPITVVLGWLTSL 541
            ||....:..|  :..||      ....|..|||:|:|.||.|.....:..:|:....:..|:.:.
Worm   468 DVPADPLGNG--DHRYFFGIGYSKPWIRCPPYLVGLLTGYLLATYGTRRIRLNWAVSIGVWIVAF 530

  Fly   542 ALLFSCLFAVYGYAADAEIPPIVEEAFYLTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQ 606
            .:...|:|:.|.|....:........|: .|.|:.|.:.:||||.|...|:||..::|:|.|:||
Worm   531 VVAGFCIFSTYDYDKGEQWSTFSRATFF-NFHRLGWGVFVCWVVGANHMGWGGPIDTFMSHPIWQ 594

  Fly   607 PLSKLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRFWCDFGFTVL---LAFAVYILIEAPFG 668
            |..:|||.|||.|..:......:.....|.|.:.|.|  :.....|||   .||....|.|.|..
Worm   595 PFGRLSYCAYIVHWMVLYFYLNVGGALHYTSAWHVFL--YISIPATVLSFVFAFFWSCLFEMPIL 657

  Fly   669 NLEGLL---LPDKRPCPP-----RPAVEESKEA 693
            .||.:|   |..:...||     :..:.|..||
Worm   658 KLEKMLIESLVGRSQMPPAKTSLKEKITEETEA 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	33/119 (28%)
		OafA	269..667	CDD:224748	128/429 (30%)
		Acyl_transf_3	282..660	CDD:280013	124/409 (30%)
oac-31	NP_503441.2	NRF	80..184	CDD:214781	33/117 (28%)
oac-31	NP_503441.2	OafA	253..659	CDD:224748	128/425 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4398
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.710