DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14205 and oac-39

DIOPT Version :9

Sequence 1:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	753	Identity:	184/753 - (24%)
Similarity:	327/753 - (43%)	Gaps:	136/753 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IVSLLVMSLALTSASIRVEHPKNSTLNVG----NPE---WQSQSYHTISRLRRLAVEFFAQYQNI 66
            :|..:|:||.:..::.....|..:...:|    :|.   .|.:.|.|...:..|.:..|::|
Worm     5 LVLFVVISLGIVPSNGLEFDPNKAMALLGELMAHPREVMEQLEKYKTSDLIAALGIHSFSKY--- 66

  Fly    67 TISDLYRD-------------KEIRLPTTDDLRCLADLQTLAKDVSDRKLWALRMIDSWGTFPSG 118
            |||:...:             :.::..||.....:.|:        ::..:.:.|:|:.|...||
Worm    67 TISEECHEELAFLGYGMIDVARHVKHQTTAAPSTMTDV--------EKTRYLIPMMDAAGKIGSG 123

  Fly   119 ILYGNVIDLGNFDECLGID-HAVTSTHNVQGKY--CLSKLQL-------ASSIPTFLALKTAVCF 173
            |..|:::..|.|.||..:. |:.:....::|.|  .|..:::       :..:|   .:...:|.
Worm   124 IARGHILSAGAFTECKSVSMHSTSLNRTIRGDYYRILFDIKMRPNSFNDSCQLP---QIGVDICL 185

  Fly   174 PASCSADHMDTMLRRLLQNLLSIELNPDVPLVSEGTCKTAD---REPYDALTIFTIV--VLSILC 233
            |.||..:.:....|..|.  .:.||:|        .|...:   |.|......:.:|  :|||:.
Worm   186 PWSCRNEDLTDYFREALG--ATKELSP--------VCSVRNVNGRTPGFTFGTYVVVTLILSIIA 240

  Fly   234 VLMVLATV----------CDYLVCQDDQPLN-KWIKAFSARANCRILFRLVAPRSNPNVIDCLHG 287
            ..:|..||          .||...:....:. |...|||...|.:.:|::........|.. |:.
Worm   241 TSIVSCTVDYYFQNRRSKIDYERMEGSSNVGWKIFMAFSLYRNVKEIFKMKQCNKEGQVTS-LNC 304

  Fly   288 IRVLSFIWVVYGH----IYLVSFFGPNMNLVKLDTWRRSPYSMLVQHAAYSVDTFFFLSGLLMVV 348
            ||.:|.:||:.||    :.|:.     .|.|.|..:.::....|:.:|.::||||||:|..|:..
Worm   305 IRTISTVWVILGHCAAMLILIC-----TNPVDLLDFTKTYMGALLVNAYFAVDTFFFISAFLLSF 364

  Fly   349 IALRAMERTKGKLNVS-----LMYLHRYLRLTPVLALAIIVYMSILPRM-GDGPLYGKVNFDDYS 407
            :..:.:::.: |..:|     :.|:||..||:|...:||:....:..|| .|.|.:......| .
Worm   365 LWFKQLQKQR-KALISPGGWMMFYVHRIARLSPAYYIAILFVTFVYIRMLRDMPAFMSPAIQD-D 427

  Fly   408 KCKDTWYWTLLYVQNYA-TDEICLGHSWYLAVDMQLYIIAPILLICLYKWGKKAAAGILVAML-L 470
            .|:..::..|||::|.. |..||...|||||.|:|||:::||||:.....|  |..|:..::: |
Worm   428 TCQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSPILLLSFAIGG--AVFGLFASVVAL 490

  Fly   471 LAACLFSIMVI-------GDVSLIAISEGAMEK------------IYFSTHTRASPYLIGILFGY 516
            :|:..|:...|       .|..|     |..:.            .|::...|...|::|::.||
Worm   491 VASTAFNAYQIFFWYFPPTDYPL-----GPKDPRYNENERRYDVWNYYNPLIRCQIYIMGLVLGY 550

  Fly   517 FLHVNRGKSFKLSPITVVLGWLTSLALLFSCLFAVYGYAA-DAEIPPIVEEAFYLTFTRIAWPLG 580
            |:  .:.....::|....:.|:.||..:...:..:..|:: |...|  |:.|.|..|:|:.|...
Worm   551 FM--RKVPKININPWVDRIMWVLSLGSMVFVVLVIQDYSSGDGWTP--VQTALYSCFSRVLWGFA 611

  Fly   581 LCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNTYFSDYQVMLRF 645
            :.|:|.:..: ..||...|:|...|.||::||:.||:.|..:.....|...:..|||   .:..|
Worm   612 MSWIVISTYY-RKGLIRDFMSLSFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFS---TLSYF 672

  Fly   646 WCDFGFTVL----LAFAVYI----LIEAPFGNLEGLLL 675
            :.|   ||:    |:|.:.|    :.|.||..:|||||
Worm   673 FLD---TVIPVTALSFVIAIFWSSMFEIPFAKIEGLLL 707

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14205	NP_608323.1	NRF	102..212	CDD:214781	26/119 (22%)
		OafA	269..667	CDD:224748	116/437 (27%)
		Acyl_transf_3	282..660	CDD:280013	112/413 (27%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	26/121 (21%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	112/413 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.680