DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14204 and CG17707

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_001162627.1	Gene:	CG17707 / 5740408	FlyBaseID:	FBgn0025835	Length:	990	Species:	Drosophila melanogaster

Alignment Length:	801	Identity:	181/801 - (22%)
Similarity:	300/801 - (37%)	Gaps:	223/801 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ADYERLLDLRSLAMEFYREFRNISTADVHLLGERIGSQDLQCLADMAQFMSALSAPKAWALKMLD 102
            |:|.:|  :.:|...||.:...|.| :||          ..|..:|..:::||.:...||.|..|
  Fly   251 ANYFQL--VANLYDHFYWQISEIRT-NVH----------TGCGLEMQAYLTALHSSYEWAQKAYD 302

  Fly   103 AWGTIPSGYLIGNRVDMGNYREC--LSEGGMLTSSQ--DIQGKYCFMELPVAKWLGFTSELLAVT 163
            :.|......|.||...:|....|  |:...:....|  |:|    |....||..|...:..:.::
  Fly   303 SSGRYRGQLLFGNDKWLGQLSFCYELNRQSLTEERQHFDLQ----FYVADVALHLPSLNRSMLLS 363

  Fly   164 NIRTAVCLPSSCSAGTMELFLKQLLK-----RLLGVSDPTNLFSISETSCRIKEKAPWDGL---- 219
               ...|||.|||    ::.:|.:|.     |:|.|....|. |:.:...:|.......|:
  Fly   364 ---LGECLPKSCS----DIDVKSILSLDPYARMLTVLGAHNT-SMQQPPLQILHVRTVPGIYSHW 420

  Fly   220 -----TIFTVVLLSVFGVTVILCTLYDYFLCPEQEKLPRPIGAFSARATSRS------------L 267
                 .:|...:|::|  .|||...|......|:..:..||.|.|.:....|            |
  Fly   421 RQLKFQVFISFMLTLF--LVILVASYYQLKIDERRLVVAPIAAISGKCDGTSTKNDVFYGKSFEL 483

  Fly   268 FTI-----------------------------VEN-----TANPNV------------------- 279
            |.:                             :||     .|:||.
  Fly   484 FQMRPLGCTSSSTDDPEVDVNGNRQRCGDSSDMENGVQREFADPNTSTSVGEKSEMGDYQMETGS 548

  Fly   280 -----------------------------------------IH--CLNGMRCMSLIWVILSHEYI 301
                                                     ||  ||:|:|..|::|.::.|.|
  Fly   549 CAGGTGTYEAKQSVALHQQILLCFALQTNAKAILNINKTKEIHTACLHGLRVFSVLWTMMVHTY- 612

  Fly   302 INMKGPAINPADNLRWATQLFSSFILYGTLSVDTFFFISGLLLVSIGLRSIEKNKGKLNVP---- 362
            :.|.....|..:.:......:...|...|.|||:||||||||:..:.|:...|      .|
  Fly   613 LQMFAIGENKFERIITERSFWYQVIGNATFSVDSFFFISGLLVTMLYLKQNRK------YPTETC 671

  Fly   363 -----------LMYLHRYLRLTPIVAVAILAFYKMIPLIADGPMYD--DIGFF-----DYSGCKM 409
                       :|.|:|||||||:        |..:.:..|..:..  |...|     :::.|:|
  Fly   672 LFIKSCFSESLMMLLYRYLRLTPV--------YLFVVIFNDFAVRQGLDTSVFQPAKIEHNTCRM 728

  Fly   410 TWYWTLLYVQNY-ATSDVCVPHTWYLAVDMQLYILSPILLIALYKWGKKAAGGILVVTLLLSACL 473
            .|:..:||:.|| ..:::|:..:||:|.:||.|:::.:||....|:.|..|  |.:...|||:..
  Fly   729 YWWRNILYINNYFPQTEMCMMWSWYMANEMQFYVMAALLLALARKYFKAVA--ITLFVFLLSSWS 791

  Fly   474 FATIMVNDFPVMFKNGIQAQVVQRKIYTATHTHAAPW------LVGTMFGYLLHLMR-----GRR 527
            .:.|:...:....|       |.....:....:..||      ::|...||:|:.::     .||
  Fly   792 ISGIISLTYQYTHK-------VSLPFESFDFLYDKPWQRVGSYIMGMCTGYVLYKVKTPPLISRR 849

  Fly   528 FKLSLLATWAGWLLCLAPLFTSIFALYPYSKLLGKSPSVLQGALYYTLVRIAWPLGLCWVVFACM 592
            ..|||      |...|..|...:|.:  :...||.:.|    |.|..:...|:..||.|:|.:|.
  Fly   850 LNLSL------WACSLFVLLIVVFGV--WEGHLGTTSS----AFYVGVAHTAFGCGLVWIVLSCC 902

  Fly   593 QGYGSLANSFLSSPLWQPLSKLSYGAYIWHIFVVEVANRSVQTNTYFSNYQVMLNFWSTFGFTLL 657
            .|.....|:.||..:..|||:|:|.||:.|..::.:.:..:....:.||..::..|......:..
  Fly   903 WGLVPTVNAILSYRVMWPLSRLTYCAYLIHPIIMFICSSHMSGTVHLSNPLILTLFLGNAVVSFG 967

  Fly   658 MSYVLYVLIEAPLEALERIMF 678
            .::|:....|||:..:.:|.|
  Fly   968 CAFVISAFFEAPVIRILKICF 988

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	31/123 (25%)
		Acyl_transf_3	280..664	CDD:280013	109/419 (26%)
		OafA	283..687	CDD:224748	111/430 (26%)
CG17707	NP_001162627.1	NRF	294..399	CDD:214781	30/116 (26%)
		Acyl_transf_3	595..973	CDD:280013	106/413 (26%)
		OafA	597..985	CDD:224748	108/423 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	6	5.920