DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14204 and CG10183

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_651160.3	Gene:	CG10183 / 42782	FlyBaseID:	FBgn0039093	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	716	Identity:	341/716 - (47%)
Similarity:	451/716 - (62%)	Gaps:	40/716 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKLLAILLAMGMAMVQGA-LPTQLSNNQWTQHDVSSMADYERLLDLRSLAMEFYREF---RNIS 61
            |:..:||||..|:..:..: |..:|   ....|.:|...:        ||..:...|.   |..|
  Fly     1 MVNGIAILLLCGLGHIHASHLKEEL---HLVHHRLSRFKE--------SLFQDINHEIIDTRPSS 54

  Fly    62 TADVHLLGERIGSQDLQCLADMAQFMSALSAPKAWALKMLDAWGTIPSGYLIGNRVDMGNYRECL 126
            |:|.            |||.||.:..:.|.....|||||||:||:.|||.|.|...|:||:.|||
  Fly    55 TSDT------------QCLVDMKELFAGLKTGSYWALKMLDSWGSFPSGLLYGTFYDLGNFDECL 107

  Fly   127 SEGGMLTSSQDIQGKYCFMELPVAKWLGFTSELLAVTNIRTAVCLPSSCSAGTMELFLKQLLKRL 191
            :....::|||.|:||||||.:|:...|....|.|....|:.|.|.|:||||..:|.|..||.:..
  Fly   108 NINQEISSSQTIKGKYCFMAVPLRDVLDTGIESLEGMQIKIATCFPASCSATQIETFAGQLYQNK 172

  Fly   192 LGVSDPTNLFSISETSCRIKEKAPWDGLTIFTVVLLSVFGVTVILCTLYDYFLCPEQEKLPRPIG 256
            :..|...|: ||.|..|:..:..|||||||||||:|||..:.|:..||||||||..|: .|..|.
  Fly   173 VNSSMSFNI-SIDEDGCQTSDPVPWDGLTIFTVVILSVLTLIVVSSTLYDYFLCTTQQ-TPALIK 235

  Fly   257 AFSARATSRSLFTIVENTANPNVIHCLNGMRCMSLIWVILSHEYIINMKGPAINPADNLRWATQL 321
            ..||||.||:||.:....:|.|||.||:|:||||||||:..||::.::..|.||....|.|..:.
  Fly   236 IISARANSRALFRLEVGNSNSNVIDCLHGIRCMSLIWVVFLHEHMYSLISPNINFTYALAWLEKP 300

  Fly   322 FSSFILYGTLSVDTFFFISGLLLVSIGLRSIEKNKGKLNVPLMYLHRYLRLTPIVAVAILAFYKM 386
            .|||.::|..|||||.||.|||:....||::||..||||:|.||:||.:|:.|::|:|||.:.|:
  Fly   301 TSSFFIHGYFSVDTFLFIGGLLVSLTALRTMEKTNGKLNIPRMYVHRIIRILPVLAMAILIYVKL 365

  Fly   387 IPLIADGPMYDDIGFFDYSGCKMTWYWTLLYVQNYATSDVCVPHTWYLAVDMQLYILSPILLIAL 451
            :|:::.||::.. ||.....|...|||.||::|||||. .|:..:||||||||||||||:||..|
  Fly   366 MPVVSGGPLFKS-GFHGKEECVNGWYWDLLFIQNYATK-TCLDQSWYLAVDMQLYILSPLLLFGL 428

  Fly   452 YKWGKKAAGGILVVTLLLSACLFATIMVNDFPVMFKNGIQAQVVQRKIYTATHTHAAPWLVGTMF 516
            ||||||||..|:.:.:|||.|||||.|||.:.:..|||........|:|.||||||.|||:|.:|
  Fly   429 YKWGKKAAWAIVGIVVLLSGCLFATQMVNHYSMSIKNGGGDDEANSKLYLATHTHATPWLIGFLF 493

  Fly   517 GYLLHLMRGRRFKLSLLATWAGWLLCLAPLFTSIFALYPYSKLLGKSPSVLQGALYYTLVRIAWP 581
            ||.||:.|||:|:||.|..|:||.:.||.:||||||.||.:|......|.|..:|||||.|:.||
  Fly   494 GYFLHMNRGRKFQLSWLVLWSGWFISLAMIFTSIFATYPSAKWSAPPLSTLDESLYYTLTRVGWP 558

  Fly   582 LGLCWVVFACMQGYGSLANSFLSSPLWQPLSKLSYGAYIWHIFVVEVANRSVQTNTYFSNYQVML 646
            |.:|||||.|:|||..|||||||:|||||||:|||..:|||:||.|:.:|:|:|:||||:|.|||
  Fly   559 LAMCWVVFVCIQGYCGLANSFLSTPLWQPLSRLSYSVFIWHMFVQEINSRNVRTSTYFSSYTVML 623

  Fly   647 NFWSTFGFTLLMSYVLYVLIEAPLEALERIMFPN--RRSPPAAKDQLHIESRTEVVDQM--DQMD 707
            ||||.||.:|:||||||::||||:..|..:....  .:||...:..|     |.||:|.  |:.:
  Fly   624 NFWSDFGISLIMSYVLYLIIEAPIGGLHSLWSRTGCTKSPEVVRPVL-----TFVVNQRNGDEPE 683

  Fly   708 H 708
            |
  Fly   684 H 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	51/114 (45%)
		Acyl_transf_3	280..664	CDD:280013	214/383 (56%)
		OafA	283..687	CDD:224748	220/405 (54%)
CG10183	NP_651160.3	NRF	75..190	CDD:214781	52/115 (45%)
		OafA	245..647	CDD:224748	223/403 (55%)
		Acyl_transf_3	259..641	CDD:280013	214/383 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458052
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	12	11.800