DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14204 and CG4576

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	714	Identity:	156/714 - (21%)
Similarity:	275/714 - (38%)	Gaps:	178/714 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SALSAPKAWALKMLDAWGTIPSGYLIGNRVDMGNYRECLSEGGMLTSSQDIQGK---YCFM---- 145
            :..:|.:.:.|.|...: .:|..|      |:.:|..||         |::.|:   |||:
  Fly    16 ATFTAAQCFQLNMTQFY-EMPPLY------DLDDYDRCL---------QELNGQASTYCFVRAEV 64

  Fly   146 --ELPVAKWLGFTSELLAVTNIRT-------------AVCLPSSCS---AGTMELFLKQLLKRLL 192
              :..||.|       .|:..|..             .:|| ..|.   ||..:..|:.|...||
  Fly    65 QPDESVAAW-------RAIAEISQYDRHHFDHRQLYFGLCL-RECEASLAGLNKSELEALQAGLL 121

  Fly   193 GVSDPTN----LFSI------------------------------------SETSCRIKEKAPWD 217
            ..:...|    |||:                                    .|...::::.| |:
  Fly   122 SENAKVNVYLDLFSMEANNRQRHQRLTNACLNWRLQRRGFGVLAKSVVEYCDEAGHQVEDDA-WN 185

  Fly   218 GLTIF----TVVLLSVFGVTVIL----------CTLYDYFLCPEQEKLPRPIGAFSARATSRSLF 268
             ||.:    |:::|:..|..|.|          ....|::..|.:....:.:..||   .:|:.:
  Fly   186 -LTFYGILGTLLVLACLGSLVDLHLKRSRHDKMLKERDHYKTPPKSTAQQVLLTFS---VARNWY 246

  Fly   269 TIVENTANP--NVIHCLNGMRCMSLIWVILSHEYIINMKGPAINPADNLRWATQLFSSFILYGTL 331
            .:.:..:..  ..:..|:..:..::..||.:|...:..:....||.|..|.......:.::.|:|
  Fly   247 RLNQEPSGKIGRELRFLDCFKFFAMFMVIFAHTNWVIYESAISNPQDPERLLHTAAGTLLVSGSL 311

  Fly   332 SVDTFFFISGLLLVSIGL---RSIEKNKG------------KLNVPLMYLHRYLRLTPIVAVAIL 381
            ...|||.||||||....|   ||:|..|.            |.|:     .||:|||...|..:|
  Fly   312 ITVTFFVISGLLLTINWLAVSRSLESKKDTWSFGQYALLFVKFNI-----FRYIRLTVPYAFVLL 371

  Fly   382 ---AFYKMIPLIADGPMYDDIGFFDYSGCKMTWYWTLLYVQNYA-TSDVCVPHTWYLAVDMQLYI 442
               .:::.    |.||::..|...:...|:..|:..||||.|:. |.:.|:...||||.|...::
  Fly   372 MSGVYFEN----AGGPLWRHIFEREQLACRRNWWTNLLYVNNFVRTDERCLLQGWYLAADTHSFV 432

  Fly   443 LSPILLI---ALYKWGKKAAGGIL----VVTLLLSACLFATIMVNDFPVMF------KNGIQAQV 494
            ||.:||:   ...:|.|:...|||    ||.::|      |..:|.:|:..      |:......
  Fly   433 LSLVLLMLGHRFVRWSKQLYAGILGLFVVVPMVL------TYAMNYYPIFVPTPQTQKDSFIGDR 491

  Fly   495 VQRKIYTATHTHAAPWLVGTMFGYLLHLMRGRRFKL-----------SLLATWAGWLLCLAPLFT 548
            ...:.||::..:...:..|.:...:...:..:::||           :|:.....||....|:|.
  Fly   492 QFTEFYTSSFMNFGSYFCGVLAALVYDQLALKQYKLRELKSFQLLWFTLIPVGILWLFSAHPIFQ 556

  Fly   549 SIFALYPYSKLLGKSPSVLQGALYYTLVRIAWPLGLCWVVFACMQGYGSLANSFLSSPLWQPLSK 613
            ..:.          :||.:.||||..|.|..|..||...:.......|.:...|...|:::.|.:
  Fly   557 HYYV----------TPSAIWGALYAGLQRNIWGFGLGIFIVGMASKVGWIFRKFCCLPIFRILGR 611

  Fly   614 LSYGAYIWHIFVVEVANRSVQTNTYFSNYQVMLNFWSTFGFTLLMSYVLYVLIEAPLEALERIM 677
            |:|||:|.|:.|..:...:|:...||....:....:.|...:.|.|::|.:.:|.|:.:..::|
  Fly   612 LTYGAFIVHLLVARIVLATVREPIYFGTGMMFAFIFFTVTVSYLCSFLLAIFLELPVSSFLKLM 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	32/179 (18%)
		Acyl_transf_3	280..664	CDD:280013	106/426 (25%)
		OafA	283..687	CDD:224748	109/438 (25%)
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	104/421 (25%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	99/389 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840