DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14204 and oac-3

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	741	Identity:	204/741 - (27%)
Similarity:	320/741 - (43%)	Gaps:	164/741 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VSSMADYERLLDLRSL-AMEFYREFRNISTADVHLLGERIGSQDLQCLADMAQFMSALSAPKA-- 95
            |.|.:.|  |.|...: :.|.:..|.|.|    |:..|        |..||..::|::....|
Worm    15 VCSHSGY--LFDYGKIESFEPFSSFINYS----HVTPE--------CTKDMKTWISSIEQFTAAS 65

  Fly    96 ---------------------WALKMLDAWGTIPS-GYLIGNRVDMGNYRECLSEGGMLTSSQDI 138
                                 :|::..||:..||| |.|..:.|..|:|:||....|:     ..
Worm    66 SDCLFFKNCTASILNILKDNIYAIQQYDAFAKIPSAGLLEVSLVFDGSYQECHRISGV-----KY 125

  Fly   139 QGKYCFMELPVAKWLGFTSELL--AVTNI--RTAVCLPSSC-SAGTMELFLKQLLKRLLGVSDPT 198
            :..||::.|...:....:...:  |.|::  |.|||:|.|| |:.|::|:              .
Worm   126 ETNYCYVLLVPGRNANCSGGSIQNAGTSVAFRRAVCMPKSCASSDTVDLY--------------N 176

  Fly   199 NLFSISETSCRI--------KEKAPWDGLTIFTVVLLSVFGVTVILCTLYDYFLCPEQEKLPRPI 255
            .|.::..|:|..        |:.|.| |.:.|..|::|    ||||.|..||        |...:
Worm   177 QLSALPLTACATFCSQRDVPKDSAFW-GFSAFMFVIVS----TVILATTVDY--------LRESV 228

  Fly   256 GAFSARA--TSRSLF-------------TIVENTANPNV-IHCLNGMRCMSLIWVILSHEYIINM 304
            ...|:::  .|.||:             ||:..::.|.. |.||:.:|.:|:.||:..|  ::|.
Worm   229 YDISSKSIEKSASLYRLLYSFSFWTNASTILNVSSQPATHIKCLDCIRGLSMAWVLSGH--MLNY 291

  Fly   305 KGPAINPADNL----RWATQLFSSFILYGTLSVDTFFFISGLLLVSIGLRSIEKNKGKLNVP--- 362
                ...||.|    .:|......|.:....||||||.:|| :.|:.....::.....|..|
Worm   292 ----FAFADTLMPIKSFANYFADYFFMNAVFSVDTFFLVSG-ITVAYSFFRLKPTTKTLKSPATW 351

  Fly   363 -LMYLHRYLRLTPIVAVAILAFYKMIPLIADGPMYDDIGFFDYS-----GCKMTWYWTLLYVQNY 421
             |.|:|||:|||| ..:..:.||.:..|...||:...:  |:::     .||.:|:..|:|:.|:
Worm   352 ILFYVHRYVRLTP-PYIIFIGFYAVYALYIQGPLAASL--FNFTVLQVEACKASWWRNLIYINNF 413

  Fly   422 ATSD-VCVPHTWYLAVDMQLYILSPILLIALYKWGKKAAGGILVVTLLLSACLFATIMV------ 479
            ...: .|...:||||||.|||:::||||:|| .|...|.   |||:::  .|:.:.|:|
Worm   414 DNGENPCYGPSWYLAVDTQLYLVAPILLVAL-TWTPIAG---LVVSMV--GCIGSMIIVFILYQK 472

  Fly   480 NDFPVMFKNGIQAQVVQRKIYTATHTHAAPWLVGTMFGYLLHLMRGRRFKLSLLATWAGWLLCLA 544
            .|.|....|...:......:|....|...|:|||.:.||.|........|||.:......||.:.
Worm   473 FDMPADSFNADSSGKFNFYVYQKPWTRCPPYLVGILGGYFLSRFATSPVKLSFVKKLIPMLLAVG 537

  Fly   545 PLFTSIFALYPYSKLLGKSPSVLQGALYYTLVRIAWPLGLCWVVFACMQGYGSLANSFLSSPLWQ 609
            .:|..:.|...|.:  |...|....|.||...|..|.|.:.|::.:|..|:.....:|:|.|:||
Worm   538 LIFACLTANIGYDQ--GDHWSSWTKATYYNFSRFFWALSVLWIILSCHYGWAGPIGNFMSHPIWQ 600

  Fly   610 PLSKLSYGAYIWHIFVVEVANRSVQTNTYFSNY-QVMLNF---WSTFGFTLLMSYVL-YV----- 664
            ||.:|||.|||.|:.||          .||.|. ...|:|   |..:.:.:|.:.:| |:
Worm   601 PLGRLSYSAYIVHLMVV----------YYFLNVGDKPLHFVSTWQVYVYYILPATILTYIFAFFW 655

  Fly   665 --LIEAPLEALER----IMFPNRRSP 684
              |.|.|:..||:    |:...:|.|
Worm   656 SCLFEIPVVKLEKFLLEILLRKKRLP 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	32/143 (22%)
		Acyl_transf_3	280..664	CDD:280013	125/408 (31%)
		OafA	283..687	CDD:224748	132/438 (30%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	32/124 (26%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	126/411 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680