DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14204 and oac-50

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_001309487.1	Gene:	oac-50 / 179284	WormBaseID:	WBGene00020864	Length:	731	Species:	Caenorhabditis elegans

Alignment Length:	816	Identity:	180/816 - (22%)
Similarity:	335/816 - (41%)	Gaps:	182/816 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILLAM-GMAMVQGALPTQLSNNQWTQHDVSSMADYERLLDLRSLAMEFYREFRNISTADVHLLGE 70
            |||.: |:.:....:...|.|:.::...:    ||....::||                    ||
Worm    14 ILLQIEGVVVNDSRIQALLLNSSFSIEQL----DYRNKNEIRS--------------------GE 54

  Fly    71 RIGSQDLQCLADMAQFMSALSAPKAW----------ALKMLDAWGTIPSGYLIGN-RVDMGNYRE 124
             :.:.|| |...|.::...|::.|..          ||..|||:...|:.   |: .:..|::|:
Worm    55 -VATPDL-CKTLMKRWFQNLNSLKNGTCKNSDDCLDALDQLDAFARYPAP---GSPNIYDGSFRK 114

  Fly   125 C--LSEGGMLTSSQDIQGKYCFMELPVAKWLGFTSE---LLAVTNIRTA--VCLPSSCSA----- 177
            |  |:|.|      ..:.|||:: :...:.:....|   :|...| |||  .|.|..|..
Worm   115 CNDLNEKG------GHRRKYCYL-IQADEKMNCREEYHSILFKPN-RTAFGFCGPEICHGKDYAS 171

  Fly   178 --GTMELFLKQLLKRLLGVSDPTNLFSISETSCRIKE---KAPWDGLTIFTVVLLSVFGVTVILC 237
              |:||.....|:.|           .:....|.:::   |..:...|.|.::|    |..|...
Worm   172 MFGSMEKTFHFLMDR-----------PVCAAFCTVRDIPKKLQFYFFTAFLIML----GSVVFFS 221

  Fly   238 TLYDYF------LCPEQEKL--PRPIGAFSARATSRSLFTIVENTANPNVIHCLNGMRCMSLIWV 294
            :||||.      |..|.||:  .|.|.:||..:....:|    ....|:.|..|:.:|.::..||
Worm   222 SLYDYVRDTRYRLSSESEKVFGQRIILSFSLWSNIEFIF----QDKRPDYIRSLDCIRAITFTWV 282

  Fly   295 ILSHEYIINMKG-----PAINPADNLRWATQLFSSFILYGTLSVDTFFFISGLLLVSIGLR---S 351
            :  .:.::...|     ..::|: .:..|:...||.     |.:.|:.|:|||.:....|:   |
Worm   283 V--GQNVVGHLGFYDDKIRVDPS-KISLASSAMSSL-----LPIYTYLFMSGLTVSYTFLKGKPS 339

  Fly   352 IEKNKGKLNVPLMYLHRYLRLTPIVAVAILAFYKMIPLIADGPMYDDI-GFFDYSGCKMTWYW-T 414
            ::..|......:.:.||::|||..:.| .:.|:........|| ||.: |:...:...:..|| .
Worm   340 LDVLKQPFTWLIFFFHRWIRLTSALMV-FIGFFDAYGKYIQGP-YDALTGYSMVTQTDLCTYWMD 402

  Fly   415 LLYVQNY-ATSDVCVPHTWYLAVDMQLYILSPILLIALYKWGKKAAGGILVVTLLLSACLFATIM 478
            ::::.|: |..::|....|:||||.|..|.:|..|:|.:.  ....|.||.:        .|:::
Worm   403 IIHISNFVAVDEMCYLPAWHLAVDFQFTIFAPFFLLAFHY--STVLGTILAI--------IASLI 457

  Fly   479 VNDFPVMFKNGIQAQVVQRKIYTATHTH---------------AAPWLVGTMFGYLLHLMRGRRF 528
            .:...|.|   .....:....:|..|.|               .||:::|.:.|.:|....|.:.
Worm   458 GSGLTVFF---FLQNTILNSAFTGDHVHDDKLVEIILSKPWNQMAPYMMGMIAGCILGKHSGSKR 519

  Fly   529 KLSLLATWAGW-LLCLAPLFTSIFALYPYSKLLGKSPSVLQGALYYTLVRIAWPLGLCWVVFAC- 591
            .:..:|:...| ::.:..|...||..:        ..|.|:.||.....|..|.:.|.|::.:.
Worm   520 IIHPVASSIIWIIITVLGLVALIFGHF--------GTSQLEKALTNVSTRAVWSICLMWIIISTE 576

  Fly   592 MQGYGSLANSFLSSPLWQPLSKLSYGAYIWH----IFVVEVANRSVQTNTY---FSNYQVMLNFW 649
            ::..|.:.: :|..|.|:|..|||:.|:|.|    .|:..:...:.:..::   :.:|.:.:..:
Worm   577 LKSAGPIGH-YLEHPFWRPFGKLSFCAFIVHHMLLYFLFNIQEEAPKYTSFWHEYFHYTIPIVIY 640

  Fly   650 STFGFTLLMSYVLYVLIEAPLEALERIMFPNRRSPPAAKDQLHIESRTEV------VDQMDQMDH 708
            |.|     :::.|.|::|.|:..::|::..  :..|.:|    ||.:|:|      .|..::.|:
Worm   641 SYF-----LAFFLSVVVEIPILRIDRLIID--QFVPVSK----IEKKTDVEEDDSFKDTSNRSDN 694

  Fly   709 MDGMDQVVQ---HEKRSDIQPDLETSANK--TETDL 739
            .||..:.::   ..:.:|.|.....|.|:  .|.||
Worm   695 TDGSSKKIKKSPENQETDYQSRNAYSPNEPLLENDL 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	31/139 (22%)
		Acyl_transf_3	280..664	CDD:280013	90/418 (22%)
		OafA	283..687	CDD:224748	94/438 (21%)
oac-50	NP_001309487.1	NRF	86..195	CDD:214781	31/130 (24%)
oac-50	NP_001309487.1	Acyl_transf_3	268..646	CDD:376607	89/414 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730