DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14204 and oac-39

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	783	Identity:	184/783 - (23%)
Similarity:	319/783 - (40%)	Gaps:	165/783 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKLLAILLAMGMAMVQG-----------ALPTQLSNNQWTQHDVSSMADYERLLDLRSLAMEFY 54
            |::||.:.:.:.:.:|..           ||..:|            ||....:::    .:|.|
Worm     1 MVELLVLFVVISLGIVPSNGLEFDPNKAMALLGEL------------MAHPREVME----QLEKY 49

  Fly    55 REFRNISTADVHLLGERIGSQDLQC----------LADMAQFM--SALSAPKA--------WALK 99
            :....|:...:|...:...|:  :|          :.|:|:.:  ...:||..        :.:.
Worm    50 KTSDLIAALGIHSFSKYTISE--ECHEELAFLGYGMIDVARHVKHQTTAAPSTMTDVEKTRYLIP 112

  Fly   100 MLDAWGTIPSGYLIGNRVDMGNYRECLSEGGMLTS-SQDIQGKYCFMELPVAKWLGFTSELLAVT 163
            |:||.|.|.||...|:.:..|.:.||.|.....|| ::.|:|.|..:...:.......::...:.
Worm   113 MMDAAGKIGSGIARGHILSAGAFTECKSVSMHSTSLNRTIRGDYYRILFDIKMRPNSFNDSCQLP 177

  Fly   164 NIRTAVCLPSSCSAGTMELFLKQLL---KRLLGVSDPTNLFSISETSCRIKEKAPWDGLTIFTVV 225
            .|...:|||.||....:..:.::.|   |.|..|....|          :..:.|  |.|..|.|
Worm   178 QIGVDICLPWSCRNEDLTDYFREALGATKELSPVCSVRN----------VNGRTP--GFTFGTYV 230

  Fly   226 ----LLSVFGVTVILCTLYDYFLCPEQEKL-------PRPIG-----AFSARATSRSLFTIVENT 274
                :||:...:::.||: ||:....:.|:       ...:|     |||.....:.:|.:.:..
Worm   231 VVTLILSIIATSIVSCTV-DYYFQNRRSKIDYERMEGSSNVGWKIFMAFSLYRNVKEIFKMKQCN 294

  Fly   275 ANPNVIHCLNGMRCMSLIWVILSH--EYIINMKGPAINPADNLRWATQLFSSFILYGTLSVDTFF 337
            ....|. .||.:|.:|.:||||.|  ..:|.:   ..||.|.|.:......:.::....:|||||
Worm   295 KEGQVT-SLNCIRTISTVWVILGHCAAMLILI---CTNPVDLLDFTKTYMGALLVNAYFAVDTFF 355

  Fly   338 FISGLLLVSIGLRSIEKNKGKLNVP----LMYLHRYLRLTPIVAVAIL-AFYKMIPLIADGPMY- 396
            |||..||..:..:.::|.:..|..|    :.|:||..||:|...:||| ..:..|.::.|.|.:
Worm   356 FISAFLLSFLWFKQLQKQRKALISPGGWMMFYVHRIARLSPAYYIAILFVTFVYIRMLRDMPAFM 420

  Fly   397 -----DDIGFFDYSGCKMTWYWTLLYVQNYA-TSDVCVPHTWYLAVDMQLYILSPILLIALYKWG 455
                 ||.       |:..::..|||::|.. |.::|...:||||.|:|||::|||||::.
Worm   421 SPAIQDDT-------CQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSPILLLSF---- 474

  Fly   456 KKAAGGIL------VVTLLLSAC------LFATIMVNDFPVMFKN-------------GIQAQVV 495
              |.||.:      ||.|:.|..      .|......|:|:..|:             .....::
Worm   475 --AIGGAVFGLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENERRYDVWNYYNPLI 537

  Fly   496 QRKIYTATHTHAAPWLVGTMFGYLLHLMRGRRFKLSLLATWAG---WLLCLAPLFTSIFALYPYS 557
            :.:||          ::|.:.||.:     |:.....:..|..   |:|.|..:...:..:..||
Worm   538 RCQIY----------IMGLVLGYFM-----RKVPKININPWVDRIMWVLSLGSMVFVVLVIQDYS 587

  Fly   558 KLLGKSPSVLQGALYYTLVRIAWPLGLCWVVFACMQGYGSLANSFLSSPLWQPLSKLSYGAYIWH 622
            ...|.:|  :|.|||....|:.|...:.|:|.:.....| |...|:|...|.||::||:.||:.|
Worm   588 SGDGWTP--VQTALYSCFSRVLWGFAMSWIVISTYYRKG-LIRDFMSLSFWTPLARLSFCAYLVH 649

  Fly   623 IFVVEVANRSVQTNTYFSNYQVMLNFWSTFGFTLLMSYVLYV----LIEAPLEALERIMFPNRRS 683
            ..|:........:..|||.....  |..|......:|:|:.:    :.|.|...:|.::.....:
Worm   650 WMVLGYFFGRNHSELYFSTLSYF--FLDTVIPVTALSFVIAIFWSSMFEIPFAKIEGLLLGRSGT 712

  Fly   684 PPA 686
            |.|
Worm   713 PKA 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	28/126 (22%)
		Acyl_transf_3	280..664	CDD:280013	114/425 (27%)
		OafA	283..687	CDD:224748	119/450 (26%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	28/118 (24%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	113/424 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.680