DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14204 and oacyl

DIOPT Version :9

Sequence 1:	NP_001259710.1	Gene:	CG14204 / 32950	FlyBaseID:	FBgn0031032	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	XP_021324686.1	Gene:	oacyl / 100002566	ZFINID:	ZDB-GENE-090710-2	Length:	676	Species:	Danio rerio

Alignment Length:	705	Identity:	184/705 - (26%)
Similarity:	294/705 - (41%)	Gaps:	155/705 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 RNISTADVHLLGERIGSQDLQCLADMAQFMSAL--SAPKAWALKMLDAWGTIPSGYLIGNRVDMG 120
            ||:|               |:|:.|...|:..|  ..|..:|:.|.||:|.|.|....||....|
Zfish    23 RNVS---------------LKCVDDTMGFLMELQKETPSKFAVIMYDAFGKIGSDVEGGNVNRPG 72

  Fly   121 NYRECLSEGGMLTSSQDIQGKYCFMELPVAKWLGFTSELLAVTNIRTAVCLPSSCSAGTM----- 180
            :.|||||..|     ...:|:||.:.|...|...|           ..||:|.||:...:
Zfish    73 SLRECLSVEG-----PGFRGQYCQVFLKQDKVEYF-----------VGVCVPDSCTDSEVQTLVI 121

  Fly   181 -ELFLKQ---LLKRLLGVSDPTNLFSISETSCRIKEKAPWDGLTIFTVVLLSVFGVTVILCTLYD 241
             |.|.||   ||..:..:..|.:...|..|.|.  ..:|  .:.:..:|.|||....:.|..:..
Zfish   122 HEAFQKQQMSLLPSVPSILIPDSTLGIFMTQCH--SDSP--NIDLSAIVCLSVCCALLALPLIAS 182

  Fly   242 YFLCPEQEKLPR---PIGAFSARATSRSLFTIVEN-TANPN------------------------ 278
            .|:...:.|..|   |:...:..:.|:...|::.| :||.|
Zfish   183 IFVALIKRKQMREVAPVVGLAQTSNSKQYGTVLTNGSANQNKECSPDLDTTQTKTQNAESKQQSL 247

  Fly   279 ------------VIHC----------------LNGMRCMSLIWVILSHEYIINMKGPAINPADN- 314
                        |.:|                |||:|.:||.|:|..|    .:...|.:..||
Zfish   248 SKTVVSWLQGFSVQNCSQGLLDTEGSGRSYSSLNGIRILSLFWIISGH----TVHFSAWSHLDNE 308

  Fly   315 LRWATQLFSSFILYGT------LSVDTFFFISGLLLVSIGLRSIEKNKGKLNVPLM--YL-HRYL 370
            .||...:.::.:...|      |:||:|..:.|||.....|.:|.::...|:|.|:  || .|:.
Zfish   309 KRWKEMVENNPLYVLTFSGPVYLAVDSFLVLGGLLSAKSLLGTIRRSDNTLSVGLVVNYLFKRFK 373

  Fly   371 RLTPI---VAVAILAFYKMIPLIADGPMYDDIGFF---DYSGCKMTWYWTLLYVQNYAT-SDVCV 428
            |:.|:   :...:::.:.::|   .|..:    ||   ....||..|:..||.:.|..| :|:|.
Zfish   374 RIQPLHLFIVCLVISLFSVVP---RGVFW----FFAEDQVLSCKKYWWSNLLLINNLLTITDICA 431

  Fly   429 PHTWYLAVDMQLYILSPILLIALYKWGKKAAGGILVVTLLLSACLFATIMVNDF---PVMFKNGI 490
            |.||||::|.|.|..:| |||.||:..|.|...:.||.|:||:...|  ::..|   ||.....:
Zfish   432 PWTWYLSIDFQFYATTP-LLIFLYRMNKCALVVVSVVLLMLSSVTGA--LITSFLHLPVHQPTTL 493

  Fly   491 QAQVVQRKIYTATHTHAAPWLVGTMFGYLLHLMRGRRFKLSLLATWAGWLLCLAPLFTSIFALYP 555
            ..:...:..|...:|...|:|:|.:.|..:...:....|....|. .|||..|     |:.||
Zfish   494 AYESYFQYYYNKPYTRYGPYLLGVLAGIYMTTKKEALIKHQWQAV-IGWLCSL-----SVMAL-- 550

  Fly   556 YSKLLGKS-------PSV-LQGALYYTLVRIAWPLGLCWVVFACMQGYGSLANSFLSSPLWQPLS 612
               |:|.:       |.: :..|:|..:.|..|.|.|.|::.||.:|||...::|||..||.|||
Zfish   551 ---LVGLAYVLRDVPPHLSIPHAIYQGIHRSLWALALIWIILACEEGYGGFVDTFLSLSLWAPLS 612

  Fly   613 KLSYGAYIWHIFVVEVANRSVQTNTYFSNYQVMLNFWSTFGFTLLMSYVLYVLIE 667
            .:|:..|:.|..::.:.|...:...:::::.....|......::.:.|||.||||
Zfish   613 NISFACYLIHPIIIILYNGKQEITMHYTDFNFFYLFLGHLVLSIFIGYVLTVLIE 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14204	NP_001259710.1	NRF	94..209	CDD:214781	36/123 (29%)
		Acyl_transf_3	280..664	CDD:280013	117/427 (27%)
		OafA	283..687	CDD:224748	120/413 (29%)
oacyl	XP_021324686.1	NRF	48..120	CDD:214781	27/87 (31%)
oacyl	XP_021324686.1	OafA	273..668	CDD:224748	120/420 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588164
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.660