Protein Alignment Tao and map4k6

DIOPT Version :10

• Sequence 1: NP_728267.1
• Gene: Tao / 32948
• FlyBaseID: FBgn0031030
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001038725.1
• Gene: map4k6 / 692287
• ZFINID: ZDB-GENE-060512-339
• Length: 889
• Species: Danio rerio
• Alignment Length: 713
• Identity: 190/713 - (26%)
• Similarity: 278/713 - (38%)
• Gaps: 191/713 - (26%)

  Fly    22 DPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPN 86
            ||...:|.:..||.|::|.|:.||...|..|.|||.:..   ...:....|..||..::...|.|
Zfish    10 DPLDDYELIHRIGSGTYGDVFKARSIKTSVIAAIKVVKL---DPGDDISSIQNEITMMKDCTHKN 71

  Fly    87 TIEYKGCYLRESTAWLVMEYC-VGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRD 150
            .:.|.|.|||.:..|:.||:| .||..||..| ..||.|.:||.:....|.||.:||..|::|||
Zfish    72 IVAYFGSYLRNNKLWICMEFCGGGSLQDIYHV-TGPLKERQIAYVSRETLQGLHHLHQTGKMHRD 135

  Fly   151 IKAGNILLTDNGVVKLADFGSA----AIKCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLG 211
            ||..|||||:.|.|||||||.|    |......||:||||||||||.....:|.|:...|:|::|
Zfish   136 IKGANILLTERGDVKLADFGVAAEINASVAKRKSFIGTPYWMAPEVAAVEKKGGYNQLCDIWAVG 200

  Fly   212 ITCIELAERKPPYFNMNAMSALYHIAQN--ESPTL-PKNDWSDAFCSFVELCLKKMPAERPSSAK 273
            ||.|||||.:||.|:::.|.||..::::  :.|.| .||.||..|.||:::.|.|.|.:||::.|
Zfish   201 ITAIELAELQPPMFDLHPMRALMLMSKSSFQPPKLKEKNKWSTEFHSFIKMALTKNPRKRPTAEK 265

  Fly   274 LLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVD--TCETESAVGD-------- 328
            :|.||:|.:..:..:::||          ||.:|...:::...:|  ..||.|.:.|
Zfish   266 ILQHAFVMQLLTRNLVIEL----------LDTVNNPDLQQTQTMDESDLETCSVLPDKIHSLAKL 320

  Fly   329 -----TDDQQDDHA--GGDSSKSNS---ITSEHSIHSVGVSAASSQSSSSNSIPAAAQNHHHIAA 383
                 ..:||.||.  |....|...   :...:...| .:||.....|....:..|....
Zfish   321 PVQRTLSEQQFDHVKFGLPMRKETDPCPVLEAYDDWS-SISADKDSPSLLECVEEALMER----- 379

  Fly   384 HHHQQAASAAVAAAMHHHHHPHQQPPPSWPSGQQGQPVPPGAVSRNSSRHRNRPPLPNIMHSMNN 448
                   |..:.......|.|:::.             ..|.|.|.:|    .|....:.|....
Zfish   380 -------SLTIKRVSSVEHSPNEED-------------KYGTVKRMAS----SPQSTALCHQEKK 420

  Fly   449 NVTPTNSASVVPAPA--------PAPVLPPPI---------SVLPHLSA------------MGHV 484
            ..||    |.:|:|.        |:|...|.:         |.|.|:|.            :.|.
Zfish   421 APTP----SSIPSPIIGSSSLKNPSPNTNPSLLSESALLIGSTLSHMSLITNSCLFTDSSFLSHS 481

  Fly   485 GGGG----TGTGGSGGGSPASGGPLADRIQPVQPRYLTTPAAQAAVYAASSASSQQAISNAVNDH 545
            ...|    |.|...||....|..|    ..||.|.:.|....|         ...:|:   ||..
Zfish   482 TSLGSLCLTPTEDPGGTRTYSTPP----DSPVSPEWSTLRRKQ---------DDSKAV---VNGL 530

  Fly   546 GPN-------------NFATIRT----TSIVTKQQKEHMQ------------EEMHE-------- 573
            .|.             |...::|    |.::.|.:.:::.            .|:||
Zfish   531 PPTPQVHMGACFSKVFNGCPLKTHCAVTWVLPKTRDQYLMLGAEEGVYTLNLNELHEDTMEKLLP 595

  Fly   574 --------------QMSG---------------YKRMRREHQAHLVKLEEKCKVDMEAHKTAL 607
                          .:||               |:|..:..|.||.....:....:.|.|.|:
Zfish   596 QRCIWLYVMNNVLMSISGKSSQLTSHSLPALFEYRRNMQRRQGHLAINAHRLSTKINARKYAM 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_728267.1	STKc_TAO	25..282	CDD:270784	112/264 (42%)
		PTZ00121	<561..984	CDD:173412	14/96 (15%)
map4k6	NP_001038725.1	STKc_MAP4K3_like	14..272	CDD:270788	111/261 (43%)
		CNH	555..869	CDD:470577	15/104 (14%)