DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and Pak

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	126/319 - (39%)
Similarity:	171/319 - (53%)	Gaps:	27/319 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSARPGS---------LKDPEIAD----LFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIV 53
            |:|.|.:         :.|.||.:    :.:..||.:.:..:.:||.|:.|.||.|..:.|...|
  Fly   528 PAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEV 592

  Fly    54 AIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCV-GSASDIIEV 117
            |||:|:.:   .|.|.:.|:.||..:|:..|||.:.|...||.....|:||||.. ||.:|:  |
  Fly   593 AIKQMNLS---QQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDV--V 652

  Fly   118 HKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANS-- 180
            .:..:.|.:|||:|..||..|.:||:...||||||:.||||..:|.|||.|||..|...|..|
  Fly   653 TETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKR 717

  Fly   181 --FVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPT 243
              .|||||||||||:   ...||..|||:|||||..||:.|.:|||.|.|.:.|||.||.|..|.
  Fly   718 TTMVGTPYWMAPEVV---TRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPE 779

  Fly   244 LPKND-WSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVR 301
            :.:.| .|.||..|::.||:.....|.|:..||.|.::...|....|..||...|.|.:
  Fly   780 IKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATK 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	112/262 (43%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	112/258 (43%)
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	114/267 (43%)
		S_TKc	566..817	CDD:214567	112/258 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940