DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tao and wts

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_733403.1	Gene:	wts / 43651	FlyBaseID:	FBgn0011739	Length:	1105	Species:	Drosophila melanogaster

Alignment Length:	770	Identity:	146/770 - (18%)
Similarity:	252/770 - (32%)	Gaps:	245/770 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 KMPAERPSSAKLLTH-------AYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTC 320
            |.|.|.|.||.....       |.|.:|.:.::   .::.....|..:.|....||...||.:..
  Fly    66 KQPMEPPPSASPAPDVVIPPPPAIVGQPGAGSI---SVSGVGVGVVGVANGRVPKMMTALMPNKL 127

  Fly   321 ETESAVGDTDDQQDDH---------AGGDSSKSNSITSEH----SIHSVGVSAAS-----SQSSS 367
            ..:.::  ..|....|         :|..||:|:|..|.|    |..:||....:     |.|..
  Fly   128 IRKPSI--ERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQPSSRTVGNPGGNGGFSPSPSGF 190

  Fly   368 SNSIPAAAQNHHHIAAHHHQQAASAAVAAAMHHHHHPHQQPPPSWPSGQQGQPVPPGA---VSRN 429
            |...|.|       ....:..|.|||.             |||         ||||.:   |.|.
  Fly   191 SEVAPPA-------PPPRNPTACSAAT-------------PPP---------PVPPTSQAYVKRR 226

  Fly   430 SSRHRNRPPLPNIMHSMNNNVTPTNSASVVPAPAPAPVLPPPISVLPHLSAMGHVGGGGTGT--- 491
            |....||||.          :.|.......|......:..|...:...|.::....|||:|.
  Fly   227 SPALNNRPPA----------IAPPTQRGNSPVITQNGLKNPQQQLTQQLKSLNLYPGGGSGAVVE 281

  Fly   492 --------GGSGGGSPASGGP-----LADRIQPVQPR---YLTTPAAQAAVYAASSASSQQAISN 540
                    ||:||.:|....|     :..|..|.|.:   |..:|:  :.:|:|:||.|...|:.
  Fly   282 PPPPYLIQGGAGGAAPPPPPPSYTASMQSRQSPTQSQQSDYRKSPS--SGIYSATSAGSPSPITV 344

  Fly   541 AV---------------NDHGPNNFATIRTTSIVTKQQKEHMQEEMHEQMSGYKRMRREHQAHLV 590
            ::               ....|....::::|.:    ||..:|..:..|..
  Fly   345 SLPPAPLAKPQPRVYQARSQQPIIMQSVKSTQV----QKPVLQTAVAPQSP-------------- 391

  Fly   591 KLEEKCKVDMEAHKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQ 655
              ......:...|..|....|              ..|....|:::.:..:||.::.|:....|.
  Fly   392 --SSASASNSPVHVLAAPPSY--------------PQKSAAVVQQQQQAAAAAHQQQHQHQQSKP 440

  Fly   656 ENDR--KVYDLNRKKEYKANKERWKRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRMLQAQ 718
            ....  .:..||.|... .....:.:.:....:|..:|:. ..|.|:..::|.:.|::|:..|.|
  Fly   441 PTPTTPPLVGLNSKPNC-LEPPSYAKSMQAKAATVVQQQQ-QQQQQQQQVQQQQVQQQQQQQQQQ 503

  Fly   719 KQYIELEMRKFKRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQ 783
            .|.:.:...:.:|:|        ||:.||:                      :|.|..|||..:.
  Fly   504 LQALRVLQAQAQRER--------DQRERDQ----------------------RERERDQQKLANG 538

  Fly   784 LREEQI--------NKQHDTELHNQKDYMDRIK-------------------------------- 808
            ....|:        |..:::|:.......:.|:
  Fly   539 NPGRQMLPPPPYQSNNNNNSEIKPPSCNNNNIQISNSNLATTPPIPPAKYNNNSSNTGANSSGGS 603

  Fly   809 --------------KELVRKHAVELRQQPKSLKQKELQIRKQFRETCKTQTKQYKRYKAQVLQTT 859
                          |::  |||..:.::.|..|:|| :.||:||         .::|..|..:..
  Fly   604 NGSTGTTASSSTSCKKI--KHASPIPERKKISKEKE-EERKEFR---------IRQYSPQAFKFF 656

  Fly   860 PKEQQKEVIKQLKEEKHRKLTLLGEQYEQSIADMFQSQSYKL---DESQVIECQR 911
            .::..:.|||..::..:||..|..|.::..:.|..|.:..|:   .||..|..:|
  Fly   657 MEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKR 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	8/25 (32%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	7/23 (30%)
wts	NP_733403.1	STKc_LATS	717..1078	CDD:270749
wts	NP_733403.1	S_TKc	719..1020	CDD:214567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910