DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and akt2l

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_021334818.1	Gene:	akt2l / 403146	ZFINID:	ZDB-GENE-040121-5	Length:	625	Species:	Danio rerio

Alignment Length:	283	Identity:	72/283 - (25%)
Similarity:	124/283 - (43%)	Gaps:	36/283 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FEDLREIGHGSFGAV----------YYARCNLTREIVAIK-KMSYTGKQSQEKWQDILKEIRFLR 80
            |:.|:.:|.|:||.|          |||...|.:|::..| ::::|           :.|.|.|:
Zfish   149 FDYLKLLGKGTFGKVILVREKASGMYYAMKILRKEVIIAKDEVAHT-----------VTESRVLQ 202

  Fly    81 QLNHPNTIEYKGCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLG 145
            ...||.....|..:........||||..|.........::...||........::|.|.|.||..
Zfish   203 NTRHPFLTTLKYAFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYPHSQN 267

  Fly   146 RIHRDIKAGNILLTDNGVVKLADFG----SAAIKCPANSFVGTPYWMAPEVILAMDEGQYDGKVD 206
            .::|.:|..|::|.::|.:|:.|||    ....:....:|.|||.::||||   :::..|...||
Zfish   268 VVYRHLKLENLMLDNDGHIKITDFGLCKEGITDEATMRTFCGTPEYLAPEV---LEDNDYGRAVD 329

  Fly   207 VWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKKMPAER--- 268
            .|.||:...|:...:.|:::.:.......|...|. ..|::..:.|......| |:|.|.:|
Zfish   330 WWGLGVVMYEMMCGRLPFYSQDHERLFEQIVMEEI-RFPRSLSTHARALLTGL-LRKEPKQRLGG 392

  Fly   269 -PSSAK-LLTHAYVTRPRSDTVL 289
             |..|: ::.|.:.:..:.|.||
Zfish   393 GPDDARDVMMHKFFSGVQWDDVL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	69/274 (25%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	69/272 (25%)
akt2l	XP_021334818.1	PH_PKB	4..111	CDD:269947
		PKc_like	153..462	CDD:328722	70/279 (25%)
		PKc_like	<423..551	CDD:328722
		S_TK_X	553..621	CDD:214529
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910