DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tao and stk4

DIOPT Version :9

Sequence 1:	NP_001188672.1	Gene:	Tao / 32948	FlyBaseID:	FBgn0031030	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_989249.1	Gene:	stk4 / 394860	XenbaseID:	XB-GENE-955920	Length:	485	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	131/315 - (41%)
Similarity:	185/315 - (58%)	Gaps:	15/315 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLN 83
            || .||::|:.|.::|.||:|:||.|....|.:|||||::..     :...|:|:|||..::|.:
Frog    23 NK-QPEEVFDVLEKLGEGSYGSVYKASHKETSQIVAIKQIPV-----ESDLQEIIKEIAIMQQCD 81

  Fly    84 HPNTIEYKGCYLRESTAWLVMEYC-VGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRI 147
            ..:.::|.|.|.:.:..|:|||:| .||.||||.:.|:.|.|||.|.|....|.||.|||.:.:|
Frog    82 SLHVVKYYGSYFKNTDLWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKI 146

  Fly   148 HRDIKAGNILLTDNGVVKLADFGSAA----IKCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVW 208
            |||||||||||...|..||||||.|.    .....|:.:|||:|||||||   .|..|:...|:|
Frog   147 HRDIKAGNILLNSEGTAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI---QEIGYNCVADIW 208

  Fly   209 SLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKND-WSDAFCSFVELCLKKMPAERPSSA 272
            |||||.||:||.||||..::.|.|::.|..|..||..|.: ||..|..|:.|||.|.|..|.|:.
Frog   209 SLGITAIEMAEGKPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSAT 273

  Fly   273 KLLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAVG 327
            :||.|.::...:.:::|..||...:.|..:...|..|:::.....:..|.|:.||
Frog   274 ELLQHPFIKTAKGESILRHLINEAQDAKLKRTELKQREVEPEEEENADEDEADVG 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tao	NP_001188672.1	STKc_TAO	25..282	CDD:270784	117/262 (45%)
Tao	NP_001188672.1	S_TKc	27..280	CDD:214567	117/258 (45%)
stk4	NP_989249.1	STKc_MST1_2	26..281	CDD:132943	119/262 (45%)
stk4	NP_989249.1	Mst1_SARAH	431..478	CDD:314497
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910